{"id":"W4415898469","doi":"10.33540/3237","title":"Trust Your Gut: Diversity and Regulation of Innate Immune Responses in Intestinal Epithelial Cells","year":2025,"lang":"en","type":"dissertation","venue":"","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Stem cell; Immune system; Intestinal epithelium; Innate immune system; Wnt signaling pathway; Paneth cell; Cellular differentiation; Enteroendocrine cell; Innate lymphoid cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006634112,0.0004044917,0.0005081834,0.0005717684,0.0007905636,0.002130206,0.0003658721,0.001071591,0.006839199],"category_scores_gemma":[0.0009862798,0.0002360221,0.0003820507,0.0005352861,0.0007740046,0.002038329,0.00164091,0.001741617,0.002503667],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006282916,"about_ca_system_score_gemma":0.0007164822,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006031414,"about_ca_topic_score_gemma":0.001065169,"domain_scores_codex":[0.9991897,0.0001929866,0.00003998292,0.0001608111,0.0002413886,0.0001750221],"domain_scores_gemma":[0.9991616,0.00009011635,0.0001204406,0.00008059265,0.0002036795,0.0003435556],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000829721,0.00009048918,0.009949965,0.001941357,0.0001303002,0.002700087,0.001849199,0.0002502587,0.7051809,0.01616685,0.03459414,0.2263167],"study_design_scores_gemma":[0.0001423741,0.001222179,0.05303319,0.0009274862,0.0002364349,0.0114068,0.003783895,0.0009834211,0.1282913,0.01339521,0.7863998,0.0001779344],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.3970043,0.3863955,0.037547,0.04689077,0.01341525,0.0002053943,0.003231812,0.001913715,0.1133962],"genre_scores_gemma":[0.8574938,0.0702875,0.007893683,0.006762634,0.001454807,0.0001296221,0.001531546,0.0003409542,0.05410554],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006839199,"threshold_uncertainty_score":0.02287936,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02595227223393413,"score_gpt":0.289504458152372,"score_spread":0.2635521859184378,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}