{"id":"W4415898975","doi":"10.1136/jitc-2025-sitc2025.0407","title":"407 Relationships between lymphocyte counts and clinical outcomes in patients with recurrent glioblastoma treated with pembrolizumab","year":2025,"lang":"","type":"article","venue":"Regular and Young Investigator Award Abstracts","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Pembrolizumab; Lymphocyte; Glioblastoma; Immunotherapy; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004334058,0.0005363323,0.001006468,0.000362567,0.000224804,0.0001157653,0.00009351363,0.0003904839,0.00001327343],"category_scores_gemma":[0.0004158479,0.0003508064,0.00009728505,0.0004720032,0.0006316803,0.000181041,0.00006103223,0.0005200428,0.00002728074],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003094052,"about_ca_system_score_gemma":0.0006533494,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000154401,"about_ca_topic_score_gemma":0.0002122233,"domain_scores_codex":[0.9970893,0.0002188823,0.0009274347,0.0007769633,0.0004943077,0.0004931405],"domain_scores_gemma":[0.997877,0.0003544655,0.0003160592,0.0004577107,0.0001817701,0.0008129771],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001025784,0.0007286484,0.9914556,0.0001616222,0.0008429795,0.0001497501,0.0001014456,0.000005108195,0.000001037354,0.0001444228,0.0004174239,0.004966241],"study_design_scores_gemma":[0.01632279,0.001965179,0.9763168,0.001928702,0.001449033,0.00001613288,0.00007368274,0.00004309226,0.0001303593,0.00009451311,0.001302759,0.0003569882],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956251,0.001498446,0.000001607489,0.0007528117,0.0002352695,0.001035785,0.0000892788,0.00004574375,0.0007159636],"genre_scores_gemma":[0.9986466,0.0004707585,0.0001542011,0.0001043986,0.00006287179,0.00003620339,0.00009854799,0.00004467698,0.0003817741],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01529701,"threshold_uncertainty_score":0.9998944,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0181503573050157,"score_gpt":0.2713920643638617,"score_spread":0.253241707058846,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}