{"id":"W4415899917","doi":"10.1101/2025.11.04.686467","title":"Host range and zoonotic potential linked to P-like fimbrial adhesin specificity in avian pathogenic <i>Escherichia coli</i>","year":2025,"lang":"","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada","keywords":"Bacterial adhesin; Fimbria; Virulence; Pilus; Glycan; Antigen; Gene; Plasmid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001204314,0.0001580258,0.0001164922,0.0002262052,0.00008074496,0.0002122918,0.00009446478,0.0002100232,0.0005815687],"category_scores_gemma":[0.000125268,0.00009656301,0.0001377521,0.0001030886,0.0001527903,0.00009423778,0.0001274817,0.0002430666,0.00007733009],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001441483,"about_ca_system_score_gemma":0.00007496144,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001310438,"about_ca_topic_score_gemma":0.0011395,"domain_scores_codex":[0.9998686,0.00002057293,0.000009765075,0.00004121065,0.00001923713,0.00004055757],"domain_scores_gemma":[0.9998616,0.00002605311,0.00006045168,0.000008688217,0.0000143405,0.00002890204],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001717254,0.00003550649,0.009261036,0.00001994684,0.000007038662,0.00008870568,0.00002714434,0.00002227093,0.9895997,0.00002282508,0.00001464848,0.0007293503],"study_design_scores_gemma":[0.00001464969,0.00126152,0.8271382,0.00001286646,0.00003785816,0.00157573,0.0002483506,0.0007249815,0.168345,0.00005071134,0.0005795431,0.00001048524],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.999629,0.0001072743,0.00008229838,0.000009155032,8.533456e-7,0.000002042467,0.00005059335,0.00000239487,0.0001163666],"genre_scores_gemma":[0.9996532,0.00004242978,0.0001163047,0.00001013647,9.24177e-7,0.000001857351,0.00008979644,8.911326e-7,0.00008433954],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001310438,"threshold_uncertainty_score":0.002605557,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01127919974634351,"score_gpt":0.2317404240092743,"score_spread":0.2204612242629308,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}