{"id":"W4415900084","doi":"10.1016/s2352-3026(25)00256-x","title":"Patient-reported outcomes with belantamab mafodotin, pomalidomide, and dexamethasone versus bortezomib, pomalidomide, and dexamethasone in patients with relapsed or refractory multiple myeloma (DREAMM-8): a phase 3, open-label, randomised controlled trial","year":2025,"lang":"en","type":"article","venue":"The Lancet Haematology","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"GlaxoSmithKline","keywords":"Dexamethasone; Multiple myeloma; Refractory (planetary science); Randomized controlled trial; Phases of clinical research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002473104,0.001829894,0.003736897,0.0003752228,0.0004891059,0.001412624,0.001288202,0.002301142,0.0059167],"category_scores_gemma":[0.002882695,0.0007328256,0.003706756,0.0004509384,0.001278431,0.001497023,0.0006635044,0.003927801,0.000707226],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001116297,"about_ca_system_score_gemma":0.0008276618,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009592944,"about_ca_topic_score_gemma":0.0016072,"domain_scores_codex":[0.9985254,0.000852226,0.0001245007,0.000244654,0.0001016658,0.0001515913],"domain_scores_gemma":[0.9981006,0.0006619997,0.0006040924,0.0001125961,0.00009128015,0.0004295596],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9862009,0.001993346,0.0008740746,0.0007534584,0.002345783,0.00002051172,0.00003717273,0.0001974555,0.0005612095,0.00006216242,0.0003587379,0.006595248],"study_design_scores_gemma":[0.955083,0.03958264,0.00278866,0.00007667788,0.001438558,0.00003012262,0.00003328558,0.0002603379,0.0001465744,0.0001582116,0.0003812895,0.00002085137],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9806866,0.01393155,0.0003518591,0.0007733887,0.0006192268,0.001391058,0.0009558343,0.00005054032,0.001239922],"genre_scores_gemma":[0.9900855,0.003519996,0.0008979491,0.0007740576,0.0004991433,0.002214955,0.0008210546,0.00001172738,0.001175613],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0059167,"threshold_uncertainty_score":0.01979339,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04748470928783249,"score_gpt":0.3549491914005954,"score_spread":0.3074644821127629,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}