{"id":"W4415923705","doi":"10.1113/ep093321","title":"Potential pitfalls of using a correction to normative values for the assessment of acid–base compensation during early ascent to high altitude","year":2025,"lang":"en","type":"letter","venue":"Experimental Physiology","topic":"High Altitude and Hypoxia","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Royal University; University of Calgary; University of British Columbia, Okanagan Campus; Kelowna General Hospital","funders":"Natural Sciences and Engineering Research Council of Canada; Mount Royal University","keywords":"Effects of high altitude on humans; Hypocapnia; Respiratory compensation; Hypoxia (environmental); Hypoxic ventilatory response; Acute exposure; Respiratory alkalosis; Acclimatization","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000767078,0.0002402016,0.0003861372,0.0001005828,0.0001240293,0.00001177736,0.0002622624,0.0002292971,0.00002106378],"category_scores_gemma":[0.0000189144,0.0002043345,0.0001902156,0.00007699007,0.00007729282,0.000005666331,0.0002536996,0.0001922096,0.000002024882],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008524476,"about_ca_system_score_gemma":0.0001036999,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003502522,"about_ca_topic_score_gemma":0.00001161808,"domain_scores_codex":[0.9987003,0.0001243096,0.0003688532,0.0003969286,0.0001618435,0.0002478002],"domain_scores_gemma":[0.999192,0.0000286285,0.0002400285,0.0003512035,0.0001516092,0.00003650115],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002393063,0.0001051304,0.00001718803,0.00007828447,0.0002452741,0.000001135743,0.0002098587,0.001797094,0.9686239,0.00001548513,0.02864319,0.00002420553],"study_design_scores_gemma":[0.0006335281,0.0008987021,0.01170363,0.00008431738,0.00007381963,0.000002552335,0.0001486955,0.0001909087,0.9834986,0.00001202556,0.002538168,0.0002150255],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9865454,0.0001615309,0.006597385,0.003593898,0.001692489,0.001203336,0.0001611719,0.000008046764,0.00003667968],"genre_scores_gemma":[0.9804571,0.00001125745,0.002456139,0.01527029,0.0009936426,0.0001606748,0.0004651005,0.00002391824,0.0001618974],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02610502,"threshold_uncertainty_score":0.8332518,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0120174253576009,"score_gpt":0.305402387732562,"score_spread":0.2933849623749611,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}