{"id":"W4415925091","doi":"10.1016/j.anai.2025.08.035","title":"EFFICACY OF REMIBRUTINIB IN ANTI-IGE BIOLOGIC-NAÏVE, BIOLOGIC-EXPERIENCED, AND BIOLOGIC-REFRACTORY PATIENTS WITH CSU: REMIX-1/-2 STUDIES","year":2025,"lang":"en","type":"article","venue":"Annals of Allergy Asthma & Immunology","topic":"Urticaria and Related Conditions","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"North York General Hospital","funders":"","keywords":"Discontinuation; Placebo; Adverse effect; Post-hoc analysis; Clinical trial; Severity of illness","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002617176,0.001115338,0.00248353,0.0004452995,0.0004147878,0.0009950125,0.0006851661,0.0008580365,0.001604649],"category_scores_gemma":[0.001159083,0.0003392867,0.002891946,0.0003586091,0.0006039565,0.001017848,0.0003127622,0.002260391,0.0002830561],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005607538,"about_ca_system_score_gemma":0.0005277553,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004640241,"about_ca_topic_score_gemma":0.001452561,"domain_scores_codex":[0.9993351,0.0002947417,0.00005647503,0.0001013627,0.00006017597,0.000152108],"domain_scores_gemma":[0.999198,0.0002559981,0.0001775307,0.00008022304,0.00003844052,0.0002497929],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7215049,0.01389785,0.02689375,0.002393677,0.008871555,0.0004327522,0.0003596432,0.001932017,0.02531111,0.00044076,0.001498142,0.1964638],"study_design_scores_gemma":[0.4615218,0.3841794,0.1286211,0.0004017002,0.01009758,0.001178792,0.0003020976,0.001954312,0.005421179,0.0007543179,0.005431656,0.0001360983],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9815024,0.01614718,0.0001669513,0.00026643,0.00009587757,0.0002022133,0.0003039391,0.0000280741,0.001287081],"genre_scores_gemma":[0.9935068,0.004381064,0.0003546723,0.0003796417,0.0002002314,0.0001205531,0.0005286686,0.000009553061,0.0005189027],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002617176,"threshold_uncertainty_score":0.01384115,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02857330681760473,"score_gpt":0.3211535994775564,"score_spread":0.2925802926599517,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}