{"id":"W4415930005","doi":"10.3390/prosthesis7060142","title":"The Association Between Non-Syndromic Tooth Agenesis and MSX1, AXIN2, WNT10A, EDA, EDAR, and EDARADD Gene Mutations: A Systematic Review","year":2025,"lang":"en","type":"article","venue":"Prosthesis","topic":"dental development and anomalies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Agenesis; Association (psychology); Phenotype; Gene; Candidate gene; Tooth loss; MEDLINE; Genetic association","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004916991,0.000138113,0.0002682958,0.0000339148,0.0002539738,0.0000977797,0.0001165961,0.00008314642,0.000002179513],"category_scores_gemma":[0.000273716,0.0001018334,0.00005579269,0.0001092329,0.00004533562,0.000007549454,0.00009315285,0.00003884034,0.000008861908],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002930538,"about_ca_system_score_gemma":0.00004945954,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007479268,"about_ca_topic_score_gemma":0.00001273256,"domain_scores_codex":[0.9991088,0.00008508532,0.0002906223,0.0002358588,0.0001154038,0.0001642196],"domain_scores_gemma":[0.9995001,0.00008756968,0.000143476,0.0001769278,0.00005717604,0.00003477231],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000117583,0.0002104817,0.613645,0.1865849,0.004714138,0.000020941,0.0008791343,0.000001049632,0.1286238,0.0006151033,0.01734682,0.04724104],"study_design_scores_gemma":[0.00185091,0.0003221985,0.7337189,0.03178137,0.003412676,0.00005893012,0.0007078756,0.00003615659,0.2068333,0.0009813989,0.01886376,0.001432566],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9031109,0.09326429,0.00007770576,0.001219567,0.00009116947,0.001232064,0.00002442178,0.0000178868,0.0009619653],"genre_scores_gemma":[0.9557919,0.03181838,0.0003872302,0.000657272,0.00005095757,0.0003900188,0.00007531344,0.00001768046,0.01081125],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1548036,"threshold_uncertainty_score":0.4152645,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004115811094074766,"score_gpt":0.2247950594020841,"score_spread":0.2206792483080093,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}