{"id":"W4415950053","doi":"10.1080/21645515.2025.2579335","title":"Immune persistence and safety of the AS01 <sub>E</sub> -adjuvanted respiratory syncytial virus prefusion F protein-based vaccine in adults 50–59 years of age, including at-increased-risk adults: A randomized controlled trial","year":2025,"lang":"en","type":"article","venue":"Human Vaccines & Immunotherapeutics","topic":"Respiratory viral infections research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Cegep regional de Lanaudiere","funders":"GlaxoSmithKline","keywords":"Immunogenicity; Adverse effect; Vaccination; Randomized controlled trial; Placebo; Immune system; Virus; Cohort; Immunity","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001985905,0.0008853412,0.001770072,0.0002644397,0.0003528555,0.0007891663,0.0005725067,0.001488717,0.001632726],"category_scores_gemma":[0.001436608,0.0004488323,0.001691986,0.0002537167,0.0006295692,0.0005984115,0.0002645613,0.001546237,0.0002697064],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003580606,"about_ca_system_score_gemma":0.0007301025,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005307212,"about_ca_topic_score_gemma":0.0009840135,"domain_scores_codex":[0.9992282,0.0004283957,0.00007207665,0.0001090239,0.00006332851,0.00009889901],"domain_scores_gemma":[0.9990261,0.0002894695,0.0003115869,0.00006588288,0.0000808971,0.00022616],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.975816,0.005937695,0.002520822,0.0005769447,0.001070542,0.0000258385,0.00004664509,0.0001363476,0.003936281,0.0000351595,0.0001525053,0.009745287],"study_design_scores_gemma":[0.6975335,0.2857727,0.01211898,0.00007247577,0.001794888,0.00005963213,0.00004154435,0.0004123436,0.001511921,0.00009135595,0.0005730102,0.00001758015],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956419,0.002657527,0.000198898,0.0001028349,0.0000971293,0.0008437629,0.0001622823,0.00001499723,0.0002806472],"genre_scores_gemma":[0.9961854,0.00135686,0.0004236156,0.0002504335,0.0001445749,0.001049238,0.0002011476,0.000004018399,0.0003847321],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001985905,"threshold_uncertainty_score":0.01050264,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02285572301576652,"score_gpt":0.3072103871915086,"score_spread":0.284354664175742,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}