{"id":"W4415961367","doi":"10.1038/s41598-025-22895-2","title":"Cistromic insight into the association of retinoid X receptor with MyoD and CTCF in proliferating myoblasts","year":2025,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"CTCF; MyoD; Retinoid X receptor; Chromatin; MyoD Protein; Regulator; Retinoid X receptor beta; Histone; Histone acetyltransferase; Retinoid X receptor alpha","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000123803,0.0001180889,0.000172364,0.0002687825,0.000195977,0.0002896164,0.0001867154,0.0001881236,0.001559888],"category_scores_gemma":[0.00009729142,0.0001193352,0.0002257019,0.0001627803,0.0002127331,0.0001603963,0.0002443469,0.0003049911,0.0004093793],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003545149,"about_ca_system_score_gemma":0.0002109426,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002172916,"about_ca_topic_score_gemma":0.005151335,"domain_scores_codex":[0.999894,0.000008755509,0.000004222242,0.00003782508,0.00003373433,0.00002147985],"domain_scores_gemma":[0.999946,0.000009382748,0.00001143092,0.00000983386,0.000008884694,0.00001442216],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00003184404,0.000002804089,0.0008315971,0.00001947146,0.000003258187,0.00004390988,0.0000167946,0.00004487437,0.9975413,0.0002076169,0.00002119761,0.001235285],"study_design_scores_gemma":[0.00001446425,0.00006289289,0.05801747,0.0000125789,0.00002667384,0.0005230198,0.0001622598,0.003345552,0.9288465,0.0003989,0.008576775,0.00001281274],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9689592,0.004420906,0.01962171,0.0002043944,0.00004522739,0.00001791847,0.001071017,0.0001450279,0.005514679],"genre_scores_gemma":[0.9865705,0.0009831482,0.007068427,0.000130187,0.00000797662,0.00001374794,0.0006260978,0.00003265985,0.004567185],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002172916,"threshold_uncertainty_score":0.005218327,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002589772448479854,"score_gpt":0.2106200415305865,"score_spread":0.2080302690821066,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}