{"id":"W4415966366","doi":"10.2967/jnumed.125.270889","title":"Rechallenge and Extended [ <sup>177</sup> Lu]Lu-PSMA Therapy in Metastatic Prostate Cancer","year":2025,"lang":"en","type":"article","venue":"Journal of Nuclear Medicine","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"NOSM University; University of Toronto; Health Sciences North; University Health Network","funders":"","keywords":"Prostate cancer; Adverse effect; Clinical trial; Disease; Prostate-specific antigen; Anemia; Overall survival; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006707822,0.0004541111,0.0006889143,0.000829662,0.0001537826,0.0008608027,0.0003941965,0.0004441362,0.002532651],"category_scores_gemma":[0.001382336,0.0001573672,0.0009066914,0.0007267756,0.0002051172,0.0007390631,0.0003395994,0.0006137102,0.0007056547],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004983491,"about_ca_system_score_gemma":0.001256126,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001029902,"about_ca_topic_score_gemma":0.00302237,"domain_scores_codex":[0.9997053,0.00008908825,0.00006955968,0.00003696958,0.00008051715,0.00001850025],"domain_scores_gemma":[0.9995889,0.000238772,0.00008600335,0.00001072637,0.00006306186,0.00001255297],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0002027544,0.0000417583,0.0004667254,0.1194011,0.0004506857,0.0004902425,0.0003581659,0.0006861332,0.003606072,0.003509189,0.03456751,0.8362195],"study_design_scores_gemma":[0.00004030035,0.0002190869,0.00136618,0.02360926,0.0009469815,0.001970842,0.000134078,0.0001515748,0.001539146,0.001254183,0.968746,0.00002242836],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.0007298467,0.9963847,0.0003597841,0.0004202594,0.0001270644,0.00002987706,0.00009653073,0.00001209472,0.001839782],"genre_scores_gemma":[0.004361216,0.9935663,0.0004308469,0.0004336399,0.00008954124,0.00004484414,0.000106477,0.000003994921,0.000963012],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.002532651,"threshold_uncertainty_score":0.008472621,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04888432368160622,"score_gpt":0.3743388772120323,"score_spread":0.3254545535304261,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}