{"id":"W4415967998","doi":"10.3390/cells14211743","title":"O-GlcNAcylation: A Nutrient-Sensitive Metabolic Rheostat in Antiviral Immunity and Viral Pathogenesis","year":2025,"lang":"en","type":"review","venue":"Cells","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation; Institut national de la recherche scientifique; Canadian Institutes of Health Research; Cancer Research Society","keywords":"Effector; Immune system; Context (archaeology); Immunity; Viral pathogenesis; Inflammation; Innate immune system; Viral evolution","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003586641,0.0007548857,0.0007740314,0.001408482,0.0002502361,0.0009711842,0.0005937294,0.0009597144,0.002549674],"category_scores_gemma":[0.0003653698,0.000246024,0.0002845342,0.001790559,0.0004604794,0.001485175,0.0006877754,0.001519712,0.00181942],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006838503,"about_ca_system_score_gemma":0.0009184101,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006961693,"about_ca_topic_score_gemma":0.001403001,"domain_scores_codex":[0.9999105,0.00001492916,0.0000120916,0.00001644744,0.00003187462,0.00001433358],"domain_scores_gemma":[0.9998949,0.00003451166,0.00001658032,0.000004121921,0.0000310635,0.00001882685],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001125683,0.00004633618,0.0001755023,0.01142104,0.00006154496,0.0002018059,0.00006668618,0.0004049961,0.005046966,0.009502981,0.02601325,0.9469464],"study_design_scores_gemma":[0.000008737999,0.00006052927,0.0004793054,0.001284362,0.00004161922,0.0006066216,0.0000486319,0.00008028506,0.0008301993,0.002298834,0.9942486,0.00001233505],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001897778,0.9977908,0.0001649877,0.0002409844,0.0002287311,0.000003278632,0.00001833424,0.000008332222,0.001354728],"genre_scores_gemma":[0.0007185513,0.9982557,0.0001501121,0.0001287042,0.00008673143,0.000003593135,0.00002895682,0.000001233604,0.000626452],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002549674,"threshold_uncertainty_score":0.008529544,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01609191847470882,"score_gpt":0.3103591912972712,"score_spread":0.2942672728225624,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}