{"id":"W4415978712","doi":"10.1016/j.cbi.2025.111813","title":"Sex-specific aggressive and emotional behavior in myostatin-deficient mice: Ratio of acylated versus unacylated ghrelin is reduced, but not correlated with butyrylcholinesterase activity level, however parvalbumin expression is lost in the habenular complex","year":2025,"lang":"en","type":"article","venue":"Chemico-Biological Interactions","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Mount Saint Vincent University; Dalhousie University","funders":"Canadian Institutes of Health Research; Dalhousie University; Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement; Agence Nationale de la Recherche; Dalhousie Medical Research Foundation","keywords":"Ghrelin; Myostatin; Neurotransmitter; Hormone; Neuropeptide; Butyrylcholinesterase; Parvalbumin","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001904427,0.001186937,0.0005791691,0.001788139,0.0003521718,0.0005481176,0.0004652024,0.0007349639,0.00615131],"category_scores_gemma":[0.0002002953,0.0006360948,0.000438239,0.0003100646,0.001050737,0.000362395,0.000716626,0.001936164,0.0008672237],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004890129,"about_ca_system_score_gemma":0.0003318748,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001048632,"about_ca_topic_score_gemma":0.00270393,"domain_scores_codex":[0.9995205,0.00003896235,0.00003978146,0.0001748087,0.0001334708,0.00009242351],"domain_scores_gemma":[0.9990938,0.00005679356,0.0003451093,0.00005250533,0.00004172435,0.0004101183],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002435916,0.00003317669,0.0003717768,0.00001418122,0.000009396323,0.00009084549,0.00002928969,0.00002475731,0.9985024,0.0000864947,0.00004737833,0.0005468164],"study_design_scores_gemma":[0.0001241659,0.0004226086,0.06875554,0.00003738176,0.0001152546,0.00174926,0.000222622,0.001420443,0.9242535,0.0003135368,0.002538175,0.00004750598],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934772,0.0006581846,0.002412696,0.0002188955,0.00008402744,0.00001876254,0.001589932,0.0003521114,0.001188173],"genre_scores_gemma":[0.9715824,0.0007154842,0.003140437,0.0002484668,0.00004492376,0.000122297,0.001765171,0.0006017421,0.02177915],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00615131,"threshold_uncertainty_score":0.02057821,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05726377156666513,"score_gpt":0.3214375436788084,"score_spread":0.2641737721121433,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}