{"id":"W4415988651","doi":"10.1002/alz.70775","title":"Digital neuropathology of neurodegenerative disorders: Foundations, research advances, and future directions","year":2025,"lang":"en","type":"review","venue":"Alzheimer s & Dementia","topic":"AI in cancer detection","field":"Computer Science","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Research Chairs","funders":"National Institute of Neurological Disorders and Stroke; National Institute on Aging; National Institutes of Health","keywords":"Neuropathology; Digital pathology; Disease; Neurodegeneration; Workflow; Digital image analysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001722199,0.0008080878,0.001123597,0.004198624,0.0004362115,0.002021693,0.000985811,0.001760227,0.004560703],"category_scores_gemma":[0.002803243,0.0003171796,0.0006440728,0.003083111,0.00148796,0.003382385,0.001081182,0.002517312,0.002321206],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001224297,"about_ca_system_score_gemma":0.002478133,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002081746,"about_ca_topic_score_gemma":0.002745475,"domain_scores_codex":[0.9995104,0.0001155355,0.00007616798,0.00007921857,0.0001780834,0.00004060011],"domain_scores_gemma":[0.9972397,0.001688963,0.0002089735,0.00008438075,0.0006607359,0.0001171575],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004151462,0.00005385615,0.0003457236,0.01324649,0.00006142348,0.0001746681,0.0001190345,0.0002865003,0.0006562944,0.0114662,0.02246747,0.9510808],"study_design_scores_gemma":[0.00001037948,0.0001046817,0.00151804,0.01303071,0.0001071826,0.002071781,0.0002111633,0.0001999054,0.0006037512,0.01171097,0.9703889,0.0000425619],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001206591,0.9968978,0.0003121999,0.0009000261,0.0002720735,0.00000723649,0.00002022429,0.00001301149,0.001456716],"genre_scores_gemma":[0.0008997695,0.997427,0.0004736164,0.0004172098,0.0003302912,0.000009597499,0.00002864672,0.000002955145,0.0004107778],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004560703,"threshold_uncertainty_score":0.01525712,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05172283799378433,"score_gpt":0.3708466829135247,"score_spread":0.3191238449197404,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}