{"id":"W4416023742","doi":"10.1016/j.jhepr.2025.101671","title":"Circulating HBV RNA and hepatitis B core-related antigen as determinants of HBsAg loss in persons with HIV in Europe","year":2025,"lang":"en","type":"article","venue":"JHEP Reports","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"European AIDS Treatment Network; Swiss HIV Cohort Research Foundation; Schweizerische Akademie der Medizinischen Wissenschaften; Gottfried und Julia Bangerter-Rhyner-Stiftung; Danmarks Grundforskningsfond; MSD Sharp and Dohme; Agence Nationale de la Recherche; FP7 Coordination of Research Activities; Inselspital, Universitätsspital Bern; Janssen Scientific Affairs; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Gilead Sciences; Sidaction; Bristol-Myers Squibb","keywords":"HBsAg; Hepatitis B virus; Human immunodeficiency virus (HIV); Hepatitis B; Antigen; RNA; Antibody; Transmission (telecommunications)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001325201,0.0001939707,0.0002420398,0.0007274727,0.0003016416,0.0008056356,0.000255575,0.0004019248,0.000958226],"category_scores_gemma":[0.002182126,0.0001580257,0.0003992932,0.0008117186,0.0002095218,0.0003831405,0.0004789844,0.0002919601,0.00009859936],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001972414,"about_ca_system_score_gemma":0.0002533321,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004556202,"about_ca_topic_score_gemma":0.003005456,"domain_scores_codex":[0.9996524,0.0001456886,0.00004316405,0.00005993965,0.0000426587,0.00005615439],"domain_scores_gemma":[0.9990526,0.0002134861,0.0004143999,0.00004853476,0.00009234685,0.000178588],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001274975,0.00001794432,0.9983832,0.000006853797,0.00003577971,0.00004877605,0.00004459866,0.00003990876,0.00005115012,0.00001199856,0.00003356417,0.001198706],"study_design_scores_gemma":[0.00000858095,0.00006971757,0.999005,0.00002059775,0.00003828063,0.0002695505,0.0002134167,0.0001834058,0.00003913528,0.00002569557,0.000124537,0.00000201366],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992096,0.0004917214,0.00003094793,0.00002235218,0.000002619491,0.000002243454,0.00006733141,0.000001046496,0.0001721414],"genre_scores_gemma":[0.9996651,0.0001563726,0.00002672242,0.00001752178,0.000004292083,0.000001759112,0.00008297565,6.142913e-7,0.00004456934],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004556202,"threshold_uncertainty_score":0.00905937,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01569297630744075,"score_gpt":0.2860522364578238,"score_spread":0.2703592601503831,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}