{"id":"W4416023742","doi":"10.1016/j.jhepr.2025.101671","title":"Circulating HBV RNA and hepatitis B core-related antigen as determinants of HBsAg loss in persons with HIV in Europe","year":2025,"lang":"en","type":"article","venue":"JHEP Reports","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"European AIDS Treatment Network; Swiss HIV Cohort Research Foundation; Schweizerische Akademie der Medizinischen Wissenschaften; Gottfried und Julia Bangerter-Rhyner-Stiftung; Danmarks Grundforskningsfond; MSD Sharp and Dohme; Agence Nationale de la Recherche; FP7 Coordination of Research Activities; Inselspital, Universitätsspital Bern; Janssen Scientific Affairs; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Gilead Sciences; Sidaction; Bristol-Myers Squibb","keywords":"HBsAg; Hepatitis B virus; Human immunodeficiency virus (HIV); Hepatitis B; Antigen; RNA; Antibody; Transmission (telecommunications)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003117627,0.0001617409,0.000549813,0.000266852,0.00005275492,0.000009369337,0.00003555821,0.00007992524,0.00002331482],"category_scores_gemma":[0.0008222461,0.0001415068,0.00003015342,0.0007059544,0.0001556211,0.00007966113,0.00008118346,0.000191211,0.000002708244],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007967165,"about_ca_system_score_gemma":0.0002303819,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01150299,"about_ca_topic_score_gemma":0.01131309,"domain_scores_codex":[0.9984344,0.00004060789,0.0006930652,0.0003567215,0.000216486,0.000258753],"domain_scores_gemma":[0.9991822,0.00006566151,0.0002672112,0.0002870282,0.0001378933,0.00006006979],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00003060457,0.00007290384,0.9715174,0.0001514015,0.00004448411,0.02257635,0.00150129,0.000007066828,0.001160111,0.00001932855,0.00008394331,0.002835053],"study_design_scores_gemma":[0.0007151701,0.0001159846,0.9946869,0.001548924,0.00004407017,0.0009315113,0.00007520153,0.0004352098,0.0009750119,0.00006013269,0.0002864062,0.0001254834],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9861918,0.00071389,0.000004472333,0.0001613431,0.00008791485,0.0004224273,0.000004285852,0.00002839734,0.01238544],"genre_scores_gemma":[0.9983689,0.000426823,0.0002057737,0.0000950645,0.00001036935,0.00001751533,0.000006483929,0.00002119469,0.0008478962],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02316943,"threshold_uncertainty_score":0.9950795,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01569297630744075,"score_gpt":0.2860522364578238,"score_spread":0.2703592601503831,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}