{"id":"W4416056343","doi":"10.33667/2078-5631-2025-26-55-60","title":"Efficacy of dose-dense platinum-based neoadjuvant chemotherapy in patients with BRCA1/2-associated operable and locally advanced triple-negative breast cancer","year":2025,"lang":"","type":"article","venue":"Medical alphabet","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Defence Medical Centre","funders":"","keywords":"Breast cancer; Chemotherapy; Tolerability; Context (archaeology); Regimen; Disease; Stage (stratigraphy); Germline mutation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004759727,0.0001298465,0.000373625,0.0001532578,0.0001051275,0.0001985437,0.0001392684,0.0001851205,0.000295149],"category_scores_gemma":[0.001024628,0.0001105448,0.0002585999,0.0001740054,0.0001521363,0.0001590109,0.0001326347,0.000193032,0.00005268287],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002450889,"about_ca_system_score_gemma":0.0002386916,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003928621,"about_ca_topic_score_gemma":0.00106571,"domain_scores_codex":[0.9998318,0.00008446496,0.00001934635,0.00002482796,0.00002510657,0.00001445905],"domain_scores_gemma":[0.9995692,0.0001383483,0.0001666756,0.00002786891,0.00001835632,0.0000795377],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.0408937,0.001903873,0.8724862,0.00020736,0.0003527797,0.000438587,0.0001839382,0.001743332,0.008730091,0.00003805094,0.0002991742,0.07272306],"study_design_scores_gemma":[0.001530841,0.03021795,0.9626851,0.00003709174,0.0003092522,0.001162699,0.0001083599,0.001537219,0.001516824,0.00005954597,0.0008211794,0.00001395971],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988853,0.0008727371,0.00003350067,0.00002022009,0.000003991267,0.00001401245,0.00003552198,0.000001637722,0.0001329983],"genre_scores_gemma":[0.9994975,0.000250136,0.00007208054,0.00002514559,0.000008535495,0.00001111893,0.00009226972,4.088509e-7,0.00004276108],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004759727,"threshold_uncertainty_score":0.002517223,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003126390560087734,"score_gpt":0.2432940551681972,"score_spread":0.2401676646081095,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}