{"id":"W4416069933","doi":"10.1016/j.nucmedbio.2025.109409","title":"Preclinical Validation of the [18F]Florbetazine as a PET Imaging Agent for Cardiac Amyloidosis","year":2025,"lang":"en","type":"article","venue":"Nuclear Medicine and Biology","topic":"Amyloidosis: Diagnosis, Treatment, Outcomes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Optech (Canada)","funders":"","keywords":"Cardiac amyloidosis; Pet imaging; Cardiac PET; Amyloidosis; Cardiac imaging; Positron emission tomography","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002560545,0.0007296476,0.001047005,0.0003549173,0.0003541383,0.001349486,0.0008309406,0.0009338991,0.001564848],"category_scores_gemma":[0.001618124,0.0003263051,0.0005366596,0.0002866701,0.0008878832,0.0006492974,0.0003036891,0.002316882,0.0004774832],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009932843,"about_ca_system_score_gemma":0.001527102,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002640691,"about_ca_topic_score_gemma":0.003591368,"domain_scores_codex":[0.9992726,0.0003200637,0.00002963771,0.00008115556,0.000133941,0.0001626364],"domain_scores_gemma":[0.9990712,0.0002322905,0.0001797412,0.00009121629,0.0001759701,0.0002494658],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.1003218,0.05490137,0.01335326,0.0009307411,0.001301849,0.0008907208,0.0006744154,0.009832803,0.7002757,0.001500103,0.00623638,0.1097809],"study_design_scores_gemma":[0.0240758,0.5218144,0.04382138,0.0002323352,0.002098189,0.002140223,0.0004828194,0.01003237,0.3684857,0.001050374,0.02562363,0.0001427893],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9897808,0.003813623,0.002268226,0.0009704852,0.000117345,0.0005111957,0.0007878245,0.0000754705,0.001674949],"genre_scores_gemma":[0.9924305,0.002485302,0.002059825,0.0003093226,0.00007211627,0.0002826826,0.001052255,0.00003330794,0.001274634],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002640691,"threshold_uncertainty_score":0.01354158,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02672603953288676,"score_gpt":0.3483118852916599,"score_spread":0.3215858457587731,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}