{"id":"W4416082588","doi":"10.1245/s10434-025-18678-8","title":"ASO Visual Abstract: Uptake of Risk Reducing Mastectomy in Older BRCA1/2 and PALB2 Carriers Undergoing Genetic Testing After 60 Years of Age","year":2025,"lang":"en","type":"article","venue":"Annals of Surgical Oncology","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"","keywords":"Surgical oncology; Genetic testing; Mastectomy; PALB2; Risk assessment; MEDLINE","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000560601,0.0002000074,0.0002882204,0.0003796592,0.0001917514,0.0004083677,0.000326148,0.0008524376,0.03522106],"category_scores_gemma":[0.004491279,0.00008011428,0.0003863231,0.0004219106,0.0000753636,0.0002336577,0.0002291108,0.0005661106,0.0022487],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004608512,"about_ca_system_score_gemma":0.0007007802,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01056948,"about_ca_topic_score_gemma":0.01574894,"domain_scores_codex":[0.999716,0.00007593456,0.00001847,0.00005097097,0.00007527196,0.00006332662],"domain_scores_gemma":[0.9979807,0.0007769178,0.0003408479,0.00003762302,0.0002460543,0.0006179102],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01115535,0.0009271724,0.4568053,0.00130384,0.0003398725,0.0003723668,0.0001590028,0.0003898346,0.0008144618,0.0002598144,0.4314131,0.09605987],"study_design_scores_gemma":[0.0009648136,0.001080252,0.9810743,0.0003048935,0.0002444809,0.0002227145,0.0003193873,0.0004282034,0.0001325772,0.0002028069,0.01500072,0.00002472023],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7435124,0.01311129,0.0004514049,0.05763414,0.01379066,0.0003432601,0.1153959,0.0002443215,0.05551657],"genre_scores_gemma":[0.9427943,0.003414568,0.0002818792,0.009489071,0.006466161,0.0002014308,0.01397484,0.00004999769,0.02332771],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03522106,"threshold_uncertainty_score":0.1178262,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02405989697536649,"score_gpt":0.3379182222675301,"score_spread":0.3138583252921636,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}