{"id":"W4416088461","doi":"10.21203/rs.3.rs-7801202/v1","title":"Hand Function Trajectories over time in Hand Osteoarthritis in relation to pain trajectories and loss to follow-up","year":2025,"lang":"","type":"preprint","venue":"Research Square","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Arthritis Society; Dutch Arthritis Society","keywords":"Osteoarthritis; Cohort; Clinical significance; Statistical significance; Cohort study; Patient-reported outcome; Outcome (game theory)","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001429883,0.0002565415,0.0004642841,0.0009580891,0.000481184,0.00126637,0.0005610035,0.0006725685,0.005979242],"category_scores_gemma":[0.008490111,0.0002564144,0.0009975239,0.001474941,0.0002708929,0.0009839006,0.001103548,0.001057121,0.0009015867],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004162002,"about_ca_system_score_gemma":0.0007721411,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02583532,"about_ca_topic_score_gemma":0.01467433,"domain_scores_codex":[0.9994593,0.0001046707,0.00005061352,0.0001421667,0.00005945206,0.000183802],"domain_scores_gemma":[0.9959632,0.00128563,0.00124526,0.0003232668,0.0004759356,0.0007067795],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001176862,0.00006088329,0.9941757,0.00001597683,0.0001651676,0.00006441089,0.0002075289,0.0002602869,0.0001920046,0.00005706848,0.0001676668,0.003456411],"study_design_scores_gemma":[0.000004780223,0.0001251669,0.9988723,0.000008816625,0.00004182672,0.00006124102,0.0003058455,0.0003547822,0.00003317904,0.00007687442,0.0001097313,0.000005321679],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974098,0.0004259538,0.0001746072,0.00009559292,0.000007987578,0.000006701309,0.001478665,0.000007428886,0.0003932744],"genre_scores_gemma":[0.9972712,0.0001388686,0.00008119091,0.00001102299,0.000005976827,0.000008237637,0.001486779,0.000004908534,0.000991902],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02583532,"threshold_uncertainty_score":0.05136991,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02504708679839485,"score_gpt":0.3248851364453532,"score_spread":0.2998380496469583,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}