{"id":"W4416103124","doi":"10.1161/hypertensionaha.125.25021","title":"Haptoglobin Phenotype and Cardiovascular Risk: The ACCORD Blood Pressure RCT","year":2025,"lang":"en","type":"article","venue":"Hypertension","topic":"Hemoglobin structure and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Nova Scotia Health Authority; Dalhousie University","funders":"","keywords":"Haptoglobin; Blood pressure; Randomized controlled trial; Phenotype; Hemoglobin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001752568,0.0001204572,0.0001412399,0.00002078954,0.0001876039,0.00002472498,0.00009724595,0.0001479904,0.000006609745],"category_scores_gemma":[0.0001091188,0.00007806892,0.0001145676,0.00008583433,0.00005753451,0.000002856434,0.0001141494,0.0001096662,0.000004099973],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000135287,"about_ca_system_score_gemma":0.00002812779,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008876476,"about_ca_topic_score_gemma":0.00001163512,"domain_scores_codex":[0.9992707,0.00007822827,0.0001025248,0.0003106522,0.00009681233,0.0001411105],"domain_scores_gemma":[0.9993592,0.00001362278,0.00002695261,0.0004923789,0.00007678635,0.00003105638],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003417961,0.0001066238,0.02130835,0.00008580727,0.003548573,0.00001501248,0.00006645767,0.000404593,0.7569878,0.0004453692,0.05026852,0.1664211],"study_design_scores_gemma":[0.001127705,0.0001672156,0.03518238,0.00002530761,0.001922915,0.00007180421,0.00008464835,0.0002494091,0.07473316,0.000340039,0.8858703,0.0002251137],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9511926,0.04215064,0.001552173,0.0002670088,0.000575649,0.0002884943,0.00001297274,0.000028093,0.003932327],"genre_scores_gemma":[0.9971783,0.001249623,0.0001809912,0.0005927668,0.0001921282,0.00000837402,0.00002323728,0.000009991329,0.0005646003],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8356018,"threshold_uncertainty_score":0.3183558,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005498435836990697,"score_gpt":0.1924255489489249,"score_spread":0.1869271131119342,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}