{"id":"W4416127421","doi":"10.1002/exp.20240482","title":"Global Stress Responses Identify the Functionally Divergent Regulators Required for <i>Candida auris</i> Commensalism and Pathogenicity","year":2025,"lang":"en","type":"article","venue":"Exploration","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Shanghai Jiao Tong University; Program of Shanghai Academic Research Leader; Government of Jiangsu Province; State Key Laboratory of Pathogen and Biosecurity; National Natural Science Foundation of China","keywords":"Commensalism; Regulon; Virulence; Fight-or-flight response; Host (biology); Pathogenicity; Gene; Mutualism (biology); Experimental evolution","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009246847,0.0003242645,0.0002750999,0.0004457408,0.0002009653,0.0004202774,0.0001473831,0.0002396937,0.001023317],"category_scores_gemma":[0.0001586032,0.0001069129,0.0002690761,0.0003972905,0.0001921612,0.0001446829,0.000379806,0.0002813283,0.00027328],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002663156,"about_ca_system_score_gemma":0.0002328873,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001310842,"about_ca_topic_score_gemma":0.001673892,"domain_scores_codex":[0.9998497,0.00001262952,0.00001168017,0.00004958624,0.0000313318,0.00004507336],"domain_scores_gemma":[0.9998351,0.0000163086,0.00007307739,0.00001897805,0.00002215308,0.00003436552],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001410771,0.00001543746,0.007297982,0.00004147278,0.000008625993,0.00006655681,0.00004274975,0.00006867427,0.9897485,0.00005097451,0.00004611642,0.002471827],"study_design_scores_gemma":[0.0000149128,0.0003992151,0.7386245,0.00003084687,0.00006685303,0.001500143,0.0005028284,0.001339933,0.2534387,0.0002269619,0.003833293,0.00002180107],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970543,0.0005714395,0.0006313384,0.00003912512,0.000004899923,0.00001038799,0.0007391206,0.00004416361,0.0009051974],"genre_scores_gemma":[0.997793,0.0001318322,0.0006722508,0.00003336684,0.000004963219,0.000009121133,0.0009799361,0.000008362419,0.0003672056],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001310842,"threshold_uncertainty_score":0.003423333,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03196191186108261,"score_gpt":0.3319826286472673,"score_spread":0.3000207167861847,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}