{"id":"W4416133916","doi":"10.1111/dom.70263","title":"Baseline characteristics in the <scp>SYNCHRONIZE</scp> ™‐2 randomized phase 3 trial of survodutide, a glucagon receptor/ <scp>GLP</scp> ‐1 receptor dual agonist, for obesity in people with type 2 diabetes","year":2025,"lang":"en","type":"article","venue":"Diabetes Obesity and Metabolism","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; University of Toronto","funders":"Boehringer Ingelheim","keywords":"Tolerability; Type 2 diabetes; Baseline (sea); Obesity; Glucagon-like peptide 1 receptor; Diabetes mellitus; Glucagon-like peptide-1; Randomized controlled trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001926979,0.0008613389,0.001169952,0.0003066612,0.0005968132,0.0005992245,0.0003312872,0.0009592071,0.01113018],"category_scores_gemma":[0.001640932,0.0003997952,0.000993927,0.00056653,0.0003410028,0.0006625692,0.0002021749,0.001623731,0.001086901],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005139124,"about_ca_system_score_gemma":0.001183572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007134519,"about_ca_topic_score_gemma":0.001578988,"domain_scores_codex":[0.9991906,0.0002836916,0.00009103755,0.0001732853,0.000128652,0.0001327025],"domain_scores_gemma":[0.9993725,0.0001261731,0.0001649277,0.00003539241,0.00007829641,0.0002227983],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8837098,0.0130019,0.04473304,0.0009591228,0.002030783,0.0002445881,0.0001400603,0.001062762,0.007603639,0.0003082565,0.01302643,0.03317954],"study_design_scores_gemma":[0.5701717,0.1526582,0.2499308,0.0002983337,0.002859903,0.000703537,0.000193581,0.001622292,0.002921699,0.001038133,0.01745495,0.0001468798],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9457461,0.005414614,0.001669072,0.001116463,0.0003827098,0.01025217,0.02578014,0.00008682733,0.009551841],"genre_scores_gemma":[0.9470074,0.001388594,0.002483056,0.00200457,0.0001930528,0.01893719,0.01784502,0.00003992123,0.01010136],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01113018,"threshold_uncertainty_score":0.03723419,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009285637839900903,"score_gpt":0.2505621433897121,"score_spread":0.2412765055498112,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}