{"id":"W4416141170","doi":"10.25251/36zrjg92","title":"Tapinarof Cream 1% Once Daily: Maintenance of Low Disease Activity Including Pruritus Through End of the Treatment-freeInterval in a Long-term Extension Trial in Patients Down to 2 Years of Age with Atopic Dermatitis","year":2025,"lang":"","type":"article","venue":"SKIN The Journal of Cutaneous Medicine","topic":"Dermatology and Skin Diseases","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Innovaderm (Canada)","funders":"","keywords":"Atopic dermatitis; Discontinuation; Psoriasis; Skin barrier; Disease; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00103813,0.001126857,0.001856521,0.0003154745,0.0003293363,0.0008661745,0.0007433394,0.001191859,0.005016478],"category_scores_gemma":[0.0007157541,0.0003631439,0.001476445,0.0002751681,0.0005326386,0.0009477342,0.0003046981,0.003011073,0.0008139896],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004445695,"about_ca_system_score_gemma":0.0005907715,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007653477,"about_ca_topic_score_gemma":0.002552394,"domain_scores_codex":[0.9997055,0.0001067155,0.00001609642,0.00005055419,0.0000332552,0.00008784009],"domain_scores_gemma":[0.9995801,0.00007652191,0.00007347575,0.00002906143,0.00003004619,0.000210727],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8850367,0.02758689,0.002028891,0.001344662,0.001040741,0.000209859,0.0001684278,0.000341839,0.01083974,0.0002742875,0.002821289,0.06830663],"study_design_scores_gemma":[0.7211168,0.2659215,0.009230333,0.0001151033,0.0003839896,0.000176779,0.00005211046,0.0003647245,0.0009292894,0.0001487339,0.001540761,0.00001985881],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9811337,0.01163755,0.0003578391,0.0004577251,0.0005759847,0.001545119,0.0008131033,0.0001425168,0.003336356],"genre_scores_gemma":[0.9867532,0.005364638,0.0006675702,0.0009172108,0.0003777377,0.001165962,0.001091553,0.00001984838,0.003642291],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005016478,"threshold_uncertainty_score":0.01678181,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01250357248406921,"score_gpt":0.2886993133716474,"score_spread":0.2761957408875783,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}