{"id":"W4416195856","doi":"10.25251/9sm0xp66","title":"Safety and Efficacy of Photodynamic Therapy with Aminolevulinic Acid 10% Topical Gel Activated by Red Light versus Aminolevulinic Acid 20% Topical Solution Activated by Blue Light for the Treatment of Actinic Keratosis on the Upper Extremities: A Blinded Randomized Study","year":2025,"lang":"","type":"article","venue":"SKIN The Journal of Cutaneous Medicine","topic":"Nonmelanoma Skin Cancer Studies","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Covenant Health","funders":"","keywords":"Photodynamic therapy; Actinic keratosis; Actinic keratoses; Intense pulsed light; Red light; Clinical endpoint; Blue light; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002369843,0.001123157,0.004175575,0.0003575678,0.0007351041,0.00003727707,0.000920968,0.0004462076,0.0004960729],"category_scores_gemma":[0.002258917,0.0004667326,0.0007597257,0.0008714128,0.001929951,0.0001018399,0.0001132495,0.001259187,0.000001785182],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008083137,"about_ca_system_score_gemma":0.0006409814,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000101905,"about_ca_topic_score_gemma":0.00007338134,"domain_scores_codex":[0.9913963,0.002186318,0.003358249,0.0007155336,0.001517112,0.000826453],"domain_scores_gemma":[0.9708165,0.02362951,0.003101516,0.001357524,0.0008583775,0.0002365821],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7608104,0.004871081,0.0001972279,0.000126897,0.01878625,0.00006069037,0.01578201,0.00001914086,0.1729805,0.00001649386,0.005091891,0.02125744],"study_design_scores_gemma":[0.4528341,0.06500273,0.0009890712,0.002917183,0.01198621,0.000432358,0.01798749,0.0003993101,0.4335599,0.0000376513,0.01335048,0.0005035754],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9102965,0.03330011,0.0003680143,0.0465421,0.001533675,0.00747521,0.00006747509,0.00001972505,0.0003971903],"genre_scores_gemma":[0.9514412,0.04532121,0.00002732795,0.0003572549,0.0006724914,0.0001626115,0.00001494738,0.0000810459,0.001921917],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3079763,"threshold_uncertainty_score":0.9997784,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02182795205974914,"score_gpt":0.3017234534958868,"score_spread":0.2798955014361377,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}