{"id":"W4416195856","doi":"10.25251/9sm0xp66","title":"Safety and Efficacy of Photodynamic Therapy with Aminolevulinic Acid 10% Topical Gel Activated by Red Light versus Aminolevulinic Acid 20% Topical Solution Activated by Blue Light for the Treatment of Actinic Keratosis on the Upper Extremities: A Blinded Randomized Study","year":2025,"lang":"","type":"article","venue":"SKIN The Journal of Cutaneous Medicine","topic":"Nonmelanoma Skin Cancer Studies","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Covenant Health","funders":"","keywords":"Photodynamic therapy; Actinic keratosis; Actinic keratoses; Intense pulsed light; Red light; Clinical endpoint; Blue light; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005978751,0.002021178,0.004372837,0.0006855312,0.0006702515,0.001562851,0.001359334,0.002734018,0.004882976],"category_scores_gemma":[0.005006112,0.00123525,0.002892493,0.0005528358,0.002126894,0.00149287,0.0005733064,0.002821161,0.0009981053],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00092369,"about_ca_system_score_gemma":0.00169829,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005468302,"about_ca_topic_score_gemma":0.0008121333,"domain_scores_codex":[0.9960716,0.002316544,0.0003503534,0.0006037119,0.0003576733,0.0003001517],"domain_scores_gemma":[0.9944233,0.001942693,0.001721293,0.0004423249,0.0005061823,0.0009642536],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9834351,0.009510934,0.0004893952,0.0002185511,0.0005065863,0.00001095595,0.00002743432,0.0001057661,0.001906467,0.00002222958,0.00008019598,0.003686383],"study_design_scores_gemma":[0.7109931,0.2849283,0.001718059,0.0000250643,0.0008358898,0.00001885649,0.00002241324,0.0003590472,0.0008115227,0.00006702629,0.0002018523,0.00001892632],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907479,0.001943373,0.0007576723,0.0001819827,0.0003405447,0.004733646,0.0004313422,0.00004703043,0.000816545],"genre_scores_gemma":[0.9895865,0.001209542,0.001641099,0.000400737,0.0005348148,0.00515692,0.0003569104,0.00001789487,0.001095522],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005978751,"threshold_uncertainty_score":0.03161901,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02182795205974914,"score_gpt":0.3017234534958868,"score_spread":0.2798955014361377,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}