{"id":"W4416198899","doi":"10.3390/bs15111552","title":"Predictors of Transition from Mild Cognitive Impairment to Normal Cognition and Dementia","year":2025,"lang":"en","type":"article","venue":"Behavioral Sciences","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institutes of Health; Genentech; IXICO; H. Lundbeck A/S; Servier; Natural Science Foundation of Liaoning Province; Eisai; Northern California Institute for Research and Education; Pfizer; Novartis Pharmaceuticals Corporation; Biogen; Eli Lilly and Company; Bristol-Myers Squibb; BioClinica; Alzheimer's Disease Neuroimaging Initiative; Meso Scale Diagnostics; Alzheimer's Association; Foundation for the National Institutes of Health","keywords":"Dementia; Cognition; Neuroimaging; Atrophy; Cognitive impairment; Alzheimer's disease; Hippocampal formation; Neuropsychology; Alzheimer's Disease Neuroimaging Initiative","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001017553,0.0004391745,0.0002955959,0.0009120326,0.0003806665,0.000749615,0.0003979968,0.0005834611,0.00110624],"category_scores_gemma":[0.003451174,0.0001754352,0.0005493789,0.0005220255,0.0002652245,0.0003483969,0.0005755923,0.0008484675,0.0002183803],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002244729,"about_ca_system_score_gemma":0.0004621315,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008097421,"about_ca_topic_score_gemma":0.00850237,"domain_scores_codex":[0.9997075,0.0000668467,0.00003916307,0.00007606503,0.0000536333,0.00005672362],"domain_scores_gemma":[0.99883,0.000278976,0.0003464077,0.00008833501,0.0001233562,0.0003329169],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001063184,0.00004504919,0.998376,0.000003961469,0.00003003354,0.0000308792,0.00002708743,0.00009473314,0.00005250785,0.00001167402,0.00005505075,0.001166561],"study_design_scores_gemma":[0.000004528497,0.00006360254,0.9989792,0.000003855315,0.00001796562,0.00008033439,0.00006688164,0.0006581301,0.00002851998,0.00004846422,0.0000461539,0.000002370694],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993343,0.0001363044,0.00007249214,0.00003330626,0.000005425723,0.000006894116,0.0001615783,0.000005481842,0.0002440656],"genre_scores_gemma":[0.9994808,0.00003929442,0.00008453128,0.00000725488,0.000005442289,0.000004116734,0.0002956498,8.255074e-7,0.00008208779],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008097421,"threshold_uncertainty_score":0.01610059,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03132354460850464,"score_gpt":0.3593635492539879,"score_spread":0.3280400046454833,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}