{"id":"W4416217551","doi":"10.1016/s0140-6736(25)01717-9","title":"A preventive care strategy to reduce moderate or severe acute kidney injury after major surgery (BigpAK-2); a multinational, randomised clinical trial","year":2025,"lang":"en","type":"article","venue":"The Lancet","topic":"Acute Kidney Injury Research","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institutes of Health; bioMérieux; Health Research Council of New Zealand; Westfälische Wilhelms-Universität Münster","keywords":"Acute kidney injury; Clinical trial; Preventive care; MEDLINE; Randomized controlled trial","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006481292,0.002022063,0.002918044,0.000568321,0.0005631507,0.001463854,0.001090704,0.00262482,0.006473557],"category_scores_gemma":[0.006291363,0.0007294738,0.003693672,0.0005408229,0.001448057,0.001363697,0.001113042,0.002581913,0.0007035891],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009966836,"about_ca_system_score_gemma":0.001672393,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001180432,"about_ca_topic_score_gemma":0.001772959,"domain_scores_codex":[0.9967577,0.002315924,0.0001987096,0.0003498851,0.0001414361,0.000236478],"domain_scores_gemma":[0.9973828,0.0007839465,0.0007970356,0.0002660514,0.0001626312,0.0006073806],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9856226,0.003600811,0.0008463237,0.0009935318,0.001941874,0.00001976802,0.00003825051,0.0002393347,0.000408573,0.0000932311,0.0005257693,0.005670143],"study_design_scores_gemma":[0.975473,0.02126802,0.001375139,0.00008329009,0.001027658,0.00001333091,0.00001193291,0.000255496,0.00008653377,0.0001036044,0.0002925616,0.000009372478],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.970962,0.009157541,0.001401944,0.002468423,0.001726724,0.009794503,0.002030225,0.00016873,0.002289944],"genre_scores_gemma":[0.9681452,0.003442653,0.004412312,0.002657275,0.001054681,0.01648376,0.001615992,0.00003436648,0.002153764],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006481292,"threshold_uncertainty_score":0.03427672,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08772907800616472,"score_gpt":0.4423918348827672,"score_spread":0.3546627568766025,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}