{"id":"W4416221126","doi":"10.1302/1358-992x.2025.13.037","title":"PRECLINICAL MODEL OF OSTEOBLASTIC-OSTEOLYTIC BONE METASTASES DEMONSTRATES SARCOPENIA WITH IMAGING BIOMARKERS","year":2025,"lang":"en","type":"article","venue":"Orthopaedic Proceedings","topic":"Bone health and treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Sarcopenia; Prostate cancer; Zoledronic acid; Docetaxel; Prostate; Osteoporosis; Atrophy; Muscle atrophy; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005020224,0.001086423,0.0008063698,0.0008294184,0.0003427483,0.0004189546,0.0006685507,0.0007998542,0.002875704],"category_scores_gemma":[0.0001254755,0.0004644881,0.00054338,0.0004280026,0.0004358173,0.0003821828,0.0003018613,0.001884614,0.001243812],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005265978,"about_ca_system_score_gemma":0.0005932652,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001425027,"about_ca_topic_score_gemma":0.003089033,"domain_scores_codex":[0.9995159,0.00004551308,0.00003498466,0.00009382956,0.000196743,0.0001129683],"domain_scores_gemma":[0.9997606,0.00001779371,0.00006989897,0.00003083024,0.00004140231,0.00007958176],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009939329,0.00256901,0.000637131,0.0001425409,0.00002459578,0.0002169025,0.0000627643,0.0003919777,0.9910203,0.0003674343,0.0005089747,0.003064471],"study_design_scores_gemma":[0.0005610057,0.03443443,0.009485625,0.00005676525,0.0001869756,0.001069214,0.0001483901,0.004063102,0.9376644,0.0003236606,0.01196843,0.00003778496],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.970888,0.003914608,0.01395784,0.0005788913,0.0003415371,0.001336438,0.002740723,0.000553066,0.005688856],"genre_scores_gemma":[0.9493616,0.004607264,0.01451477,0.0003392298,0.000065803,0.002288934,0.002965238,0.00006332142,0.02579402],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002875704,"threshold_uncertainty_score":0.009620249,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01907409691635795,"score_gpt":0.3002370001637035,"score_spread":0.2811629032473455,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}