{"id":"W4416239157","doi":"10.1002/jev2.70192","title":"From Mitochondria to Immunity: The Emerging Roles of Mitochondria‐Derived Vesicles and Small Extracellular Vesicles in Cellular Communication and Disease","year":2025,"lang":"en","type":"article","venue":"Journal of Extracellular Vesicles","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; Children's Hospital of Eastern Ontario; Institute of Infection and Immunity; University of Ottawa","funders":"Cancer Research Society","keywords":"Vesicle; Extracellular vesicles; Immune system; Mitochondrion; Intracellular; Extracellular; Cell; Microvesicles","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001251011,0.000479901,0.0006531223,0.0003870483,0.000270843,0.0001609988,0.001092207,0.0002487887,0.00001807082],"category_scores_gemma":[0.0009779909,0.0004241368,0.0002784118,0.0004144511,0.0005516093,0.00006463328,0.0006305402,0.000526885,0.000002357488],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004684309,"about_ca_system_score_gemma":0.0002870501,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001154323,"about_ca_topic_score_gemma":0.0001328064,"domain_scores_codex":[0.9962403,0.0008378876,0.001486025,0.000568279,0.000400671,0.0004668751],"domain_scores_gemma":[0.996784,0.0003708875,0.0008218205,0.00127767,0.0002985721,0.0004470404],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000830975,0.0003644691,0.006462834,0.0001190191,0.0002184735,0.00007150608,0.0011652,0.0003283873,0.978262,0.000614842,0.0004657406,0.01109657],"study_design_scores_gemma":[0.002457744,0.0002561469,0.02451186,0.0009025692,0.0004451262,0.00002244719,0.004462708,0.0006730949,0.9485644,0.008552616,0.008558638,0.000592712],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8236356,0.1678707,0.005816916,0.001889182,0.0001876937,0.0005119918,0.00003708277,0.00001145766,0.00003932168],"genre_scores_gemma":[0.9877608,0.002789107,0.008655258,0.000181111,0.0002311689,0.00002687884,0.00004696838,0.00006465662,0.0002439837],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1650816,"threshold_uncertainty_score":0.9998211,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009691531643913025,"score_gpt":0.2483256326061085,"score_spread":0.2386341009621954,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}