{"id":"W4416276010","doi":"10.1002/gcc.70090","title":"A 107 Gene Nanostring Assay Effectively Translates the Cancer Genome Atlas, and Tumour Microenvironment Gastric Cancer Molecular Classification to a Patient‐Derived Organoid Model","year":2025,"lang":"en","type":"article","venue":"Genes Chromosomes and Cancer","topic":"Ferroptosis and cancer prognosis","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Edmonton Civic Employees Charitable Assistance Fund; University of Alberta","keywords":"Organoid; Microsatellite instability; Concordance; Cancer; Tumor microenvironment; Adenocarcinoma; Gene; Population","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009876216,0.0003013518,0.0003308481,0.0006009489,0.0001594817,0.0005345759,0.0002543428,0.000269584,0.001131937],"category_scores_gemma":[0.001357534,0.0001892919,0.0003305849,0.0003359448,0.0002759466,0.0001911834,0.0003694255,0.0003096809,0.0004335581],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006240181,"about_ca_system_score_gemma":0.0003545582,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001521716,"about_ca_topic_score_gemma":0.002616326,"domain_scores_codex":[0.9993414,0.0001673856,0.00005937661,0.0001715899,0.0002229427,0.00003731958],"domain_scores_gemma":[0.9994051,0.0002290826,0.00009492409,0.0001768981,0.00006692931,0.0000270092],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000513005,0.0001203432,0.07422491,0.00008408949,0.0001076938,0.0001274702,0.00009958911,0.01474801,0.8733349,0.001249813,0.0008959927,0.03449425],"study_design_scores_gemma":[0.00004038079,0.0006300506,0.1523702,0.00002113986,0.000126373,0.0006971877,0.0001368254,0.1241332,0.70925,0.001468429,0.01107784,0.00004831252],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8913704,0.0001935489,0.1010932,0.0001107112,0.00003174719,0.0001614965,0.003404512,0.0008610071,0.002773389],"genre_scores_gemma":[0.947167,0.0001537691,0.04505751,0.00009553003,0.000005114444,0.0003144386,0.005762891,0.0001076885,0.001336084],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001521716,"threshold_uncertainty_score":0.005223095,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01195500182125101,"score_gpt":0.2500614650687669,"score_spread":0.2381064632475159,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}