{"id":"W4416298364","doi":"10.1002/acn3.70235","title":"Lessons Learned: Quality Analysis of Optical Coherence Tomography in Neuromyelitis Optica","year":2025,"lang":"en","type":"article","venue":"Annals of Clinical and Translational Neurology","topic":"Optical Coherence Tomography Applications","field":"Engineering","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Cilag; National Institute of Allergy and Infectious Diseases; Bayer Vital; Chugai Pharmaceutical; National Institutes of Health; Merz Pharmaceuticals; Mitsubishi Tanabe Pharma Corporation; Freie Universität Berlin; EMD Serono; Fondation Charcot; Syddansk Universitet; Daewoong Pharmaceutical Company; Neuraxpharm; Handok; Teva Pharmaceutical Industries; National Research Foundation of Korea; Amgen; National Research Foundation; Eisai; University of Oxford; Horizon Therapeutics; Humboldt-Universität zu Berlin; Bayer HealthCare; Acorda Therapeutics; Tel Aviv University; European Committee for Treatment and Research in Multiple Sclerosis; Alexion Pharmaceuticals; Bundesministerium für Bildung und Forschung; Biogen; Universitat Pompeu Fabra; Celgene; Argenx; Canadian Institutes of Health Research; Ipsen; Friedrich-Baur-Stiftung; Guthy-Jackson Charitable Foundation; U.S. Department of Defense; Sanofi; Allergan; AstraZeneca","keywords":"Optical coherence tomography; Neuromyelitis optica; Optic neuritis; Computed tomography","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02512552,0.0009606549,0.001300833,0.00250248,0.0005623405,0.005330741,0.00294987,0.003513468,0.002610612],"category_scores_gemma":[0.08080789,0.0003656231,0.001409418,0.00257681,0.00224269,0.004885767,0.001685271,0.004929443,0.000897947],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003413666,"about_ca_system_score_gemma":0.004448479,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0166689,"about_ca_topic_score_gemma":0.01238782,"domain_scores_codex":[0.9902811,0.004319059,0.001439862,0.001237254,0.002333869,0.0003888574],"domain_scores_gemma":[0.9300036,0.0316923,0.003949137,0.002605856,0.02826043,0.003488666],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0003969529,0.0003021937,0.1132085,0.003900908,0.00065203,0.0006533428,0.001148519,0.001466071,0.0004797431,0.00510667,0.1395343,0.7331507],"study_design_scores_gemma":[0.0008900765,0.003568658,0.4245549,0.04951807,0.001844586,0.005981481,0.02182073,0.02742033,0.00310654,0.1385556,0.3219579,0.0007812083],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.04117707,0.2058854,0.01887344,0.707137,0.01826784,0.0002472477,0.001082315,0.000287735,0.00704192],"genre_scores_gemma":[0.5266152,0.2276385,0.06170733,0.120438,0.05837208,0.0004124324,0.00112163,0.0002602397,0.003434645],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.02512552,"threshold_uncertainty_score":0.132878,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1563607045019013,"score_gpt":0.4424905749235489,"score_spread":0.2861298704216476,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}