{"id":"W4416332168","doi":"10.3390/genes16111388","title":"Distinct Morphokinetic Signature of Human Embryos with Chromosomal Mosaicism","year":2025,"lang":"en","type":"article","venue":"Genes","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women's Health Research Institute; B.C. Women's Hospital & Health Centre; Women's College Hospital","funders":"","keywords":"Embryo; Ploidy; Embryogenesis; Chromosome; Signature (topology); Karyotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004188405,0.00009921983,0.0001029578,0.00003106571,0.0000627848,0.000003843486,0.0001013561,0.0001301252,0.00002065847],"category_scores_gemma":[0.000005645719,0.00007874128,0.00003310087,0.00008478453,0.00009700369,0.00000124434,0.00005671439,0.00003590836,0.000002022997],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004945061,"about_ca_system_score_gemma":0.00004530225,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006438777,"about_ca_topic_score_gemma":0.00003609128,"domain_scores_codex":[0.9995017,0.00002248021,0.0001194315,0.0001963883,0.00004932624,0.0001106542],"domain_scores_gemma":[0.9997174,0.000003774445,0.00004758593,0.0001677752,0.00004436285,0.0000191606],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005372109,0.00002853547,0.020724,0.00002401215,0.00006106525,0.000001517642,0.00001141288,0.0000261435,0.9745887,0.0001464094,0.0006663477,0.003668148],"study_design_scores_gemma":[0.0003210497,0.0001682553,0.1454942,0.000018471,0.00001734824,0.000006208179,0.00001773009,0.000005902704,0.84891,0.0001219381,0.004824694,0.00009413213],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959074,0.001556224,0.0003671284,0.00006616412,0.00007614718,0.0001051804,0.00001074607,0.000007765503,0.001903253],"genre_scores_gemma":[0.9961523,0.00002214372,0.0004201481,0.00007340749,0.00004850761,0.00001239433,0.0002902912,0.000006078708,0.002974699],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1256787,"threshold_uncertainty_score":0.3210976,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003797565759560851,"score_gpt":0.2295374768569372,"score_spread":0.2257399110973764,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}