{"id":"W4416365351","doi":"10.1097/qai.0000000000003801","title":"Brief Report: Is Gestational Exposure to HIV and Protease Inhibitors Associated With Timing of Pubertal Onset?","year":2025,"lang":"en","type":"article","venue":"JAIDS Journal of Acquired Immune Deficiency Syndromes","topic":"HIV/AIDS Research and Interventions","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Dental and Craniofacial Research; National Institute of Child Health and Human Development; National Institute of Neurological Disorders and Stroke; National Institute of Allergy and Infectious Diseases; National Institute of Mental Health; National Heart, Lung, and Blood Institute; National Cancer Institute; National Institute on Alcohol Abuse and Alcoholism; National Institute on Deafness and Other Communication Disorders; National Institute on Drug Abuse; National Institutes of Health; Canada Research Chairs; Harvard T.H. Chan School of Public Health; Tulane University","keywords":"Human immunodeficiency virus (HIV); Gestation; Viral load; Protease; Pregnancy; Gestational age; Protease inhibitor (pharmacology); Immunopathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001362001,0.0002521802,0.0005386827,0.0007847624,0.0003993865,0.0009729656,0.0005934482,0.001066506,0.009520058],"category_scores_gemma":[0.01144586,0.000190791,0.0003449104,0.00148108,0.000310859,0.0005696876,0.0003859309,0.0008427058,0.001234629],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003676591,"about_ca_system_score_gemma":0.0006624809,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002758779,"about_ca_topic_score_gemma":0.002394244,"domain_scores_codex":[0.9991363,0.0002957224,0.0001187842,0.0002087994,0.0001471658,0.00009325744],"domain_scores_gemma":[0.9897484,0.004108424,0.00412121,0.0002427444,0.001037733,0.0007415116],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0008382141,0.00009451301,0.9196221,0.001349418,0.000247283,0.0006517701,0.0002016301,0.00008389279,0.0002215299,0.0002382371,0.02962113,0.04683036],"study_design_scores_gemma":[0.000083898,0.0005983556,0.9680798,0.001129374,0.0004061171,0.004353584,0.0005949415,0.0003523524,0.0002626672,0.0005238987,0.02358285,0.00003223156],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7021254,0.183182,0.002301495,0.04758011,0.008574708,0.000246145,0.04088371,0.0001773889,0.01492898],"genre_scores_gemma":[0.9292864,0.04396955,0.001038976,0.004036156,0.008557236,0.00009998542,0.008739475,0.00004392066,0.004228366],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009520058,"threshold_uncertainty_score":0.03184777,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01633332547239516,"score_gpt":0.3008459580436773,"score_spread":0.2845126325712821,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}