{"id":"W4416386985","doi":"10.1016/j.ijrobp.2025.09.002","title":"Less of Some and More of Another: Practice-changing Head and Neck Trials Are Redefining Long-standing Treatment Paradigms and Offering Patients More Risk-adapted Care","year":2025,"lang":"en","type":"article","venue":"International Journal of Radiation Oncology*Biology*Physics","topic":"Medical Practices and Rehabilitation","field":"Health Professions","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Head and neck; Head (geology); MEDLINE; Disease; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001509065,0.0001533843,0.0007055056,0.0002521838,0.0002086621,0.00001087388,0.0001013825,0.0002434592,0.000007005062],"category_scores_gemma":[0.004112338,0.0001184169,0.00008911247,0.0001233223,0.0001900939,0.0003732509,0.00007442701,0.0003930669,2.56264e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003960206,"about_ca_system_score_gemma":0.0002923498,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001239399,"about_ca_topic_score_gemma":0.00001903595,"domain_scores_codex":[0.9971933,0.001050192,0.001176404,0.0001936634,0.0002097276,0.0001766608],"domain_scores_gemma":[0.9900015,0.005535238,0.003618511,0.00008983294,0.0006812816,0.00007365528],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0008652,0.0001859212,0.8084374,0.0001405778,0.0005042847,0.00000378728,0.01236279,0.0001852545,0.0002296341,0.003670238,0.00003145383,0.1733835],"study_design_scores_gemma":[0.02850862,0.003742358,0.8641874,0.002926094,0.0010967,0.00002065695,0.07595239,0.00557486,0.0005166419,0.006084323,0.01101953,0.0003704931],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896266,0.003417367,0.002240117,0.002970116,0.001069823,0.0004194753,0.0001033851,0.000009351668,0.0001437034],"genre_scores_gemma":[0.9931765,0.004221132,0.001870731,0.0003177966,0.0003433694,0.00001361662,0.00002892056,0.00001278855,0.00001519243],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.173013,"threshold_uncertainty_score":0.4923149,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07690847220152981,"score_gpt":0.4602210615936225,"score_spread":0.3833125893920927,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}