{"id":"W4416387737","doi":"10.1016/j.annonc.2025.09.126","title":"LBA107 ALBAN: A phase III, randomized, open-label, international study of intravenous (iv) atezolizumab and intravesical Bacillus Calmette-Guérin (BCG) vs BCG alone in BCG-naïve high-risk, non-muscle-invasive bladder cancer (NMIBC)","year":2025,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Bladder and Urothelial Cancer Treatments","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"University of Tsukuba; Medizinische Universität Wien; Astellas Pharma; St. Antonius Ziekenhuis; Universität Wien; Russian Academy of Sciences; Cancer Research UK; Queen Mary University of London; Université Laval; Gilead Sciences; Merck KGaA; Sanofi; AstraZeneca; Pfizer","keywords":"Atezolizumab; Bladder cancer; Bacillus (shape); Bladder tumor; Standard of care; Resection","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001589038,0.001938927,0.002970979,0.0005612947,0.0004539897,0.001370154,0.001301422,0.001831802,0.006145887],"category_scores_gemma":[0.001020114,0.0008414015,0.002150084,0.0005476766,0.001444891,0.001333581,0.0004632774,0.005292501,0.001594214],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009118136,"about_ca_system_score_gemma":0.001932549,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001561453,"about_ca_topic_score_gemma":0.003493582,"domain_scores_codex":[0.9995447,0.0002088158,0.00002036609,0.00008034905,0.00003050276,0.0001152883],"domain_scores_gemma":[0.999316,0.0001476755,0.0001198902,0.00005087347,0.00003480178,0.0003308533],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9416766,0.02328936,0.0007306478,0.0005807149,0.0009186444,0.00003288098,0.00007842725,0.000497863,0.00557903,0.0001867917,0.001198375,0.02523065],"study_design_scores_gemma":[0.8866021,0.1097892,0.001446763,0.00002757817,0.0004253208,0.00003065972,0.00002972507,0.000427335,0.0005055969,0.00009618532,0.0006042615,0.00001529472],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9883619,0.003285044,0.0007457689,0.0007845964,0.0005217778,0.002490876,0.001044168,0.0002373522,0.002528405],"genre_scores_gemma":[0.9815477,0.003211178,0.002218566,0.001642646,0.0004447075,0.003382076,0.00223677,0.00006629143,0.005250021],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006145887,"threshold_uncertainty_score":0.02056009,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05070072646093399,"score_gpt":0.4062150621872794,"score_spread":0.3555143357263454,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}