{"id":"W4416411919","doi":"10.1016/j.cell.2025.07.022","title":"Mucosal viral infection elicits long-lived IgA responses via type 1 follicular helper T cells","year":2025,"lang":"en","type":"article","venue":"Cell","topic":"Viral gastroenteritis research and epidemiology","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Canada Research Chairs; Uehara Memorial Foundation","keywords":"Priming (agriculture); Major histocompatibility complex; Immunoglobulin A; Antibody; MHC class II; Immunoglobulin class switching; MHC class I; Follicular dendritic cells; Follicular phase; Viral infection","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005328773,0.0005821002,0.0002889522,0.000392924,0.0002352343,0.0004837896,0.0002310471,0.0006149035,0.001985936],"category_scores_gemma":[0.0006050264,0.0001722493,0.0003137385,0.0001159063,0.0002891267,0.0004968636,0.000566252,0.001001636,0.0005317357],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000256917,"about_ca_system_score_gemma":0.0001952917,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003679172,"about_ca_topic_score_gemma":0.0006976161,"domain_scores_codex":[0.9996291,0.0001177123,0.00002192487,0.00005780301,0.00003948675,0.0001339043],"domain_scores_gemma":[0.9995663,0.0001473392,0.00005925024,0.00005820772,0.00007105825,0.00009793693],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001045922,0.000273679,0.01348621,0.0002754036,0.00003174162,0.0006374233,0.0003649623,0.0002397552,0.9554958,0.0002720443,0.0004676951,0.02740942],"study_design_scores_gemma":[0.001028906,0.0242183,0.3659779,0.0005190419,0.0003780689,0.007454105,0.006833021,0.00733251,0.5463793,0.002725589,0.03703761,0.0001155969],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932591,0.00204645,0.001472018,0.0001577557,0.0001401607,0.00007004736,0.0001128771,0.00005872059,0.002682985],"genre_scores_gemma":[0.9952105,0.0007028485,0.001048618,0.0001377544,0.0002276031,0.00004583202,0.0001440711,0.00001234683,0.002470473],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001985936,"threshold_uncertainty_score":0.006643593,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02228820867414443,"score_gpt":0.325391749288898,"score_spread":0.3031035406147535,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}