{"id":"W4416422806","doi":"10.2196/86380","title":"Automated Optic Disc Tilt Classification in Fundus Photography: Segmentation and Elliptical Ratio Across External Clinical Validation (Preprint)","year":2025,"lang":"en","type":"article","venue":"JMIR Formative Research","topic":"Retinal Imaging and Analysis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Tilt (camera); Segmentation; Optic disc; Fundus (uterus); Optic cup (embryology); Glaucoma; Optic disk; Pixel","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004927855,0.001057038,0.0007470719,0.001777231,0.0004788531,0.001773062,0.001136125,0.00117756,0.002883795],"category_scores_gemma":[0.01233344,0.0003025595,0.001031321,0.0006533636,0.000529371,0.0006074903,0.001148034,0.0005660774,0.002492836],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009183222,"about_ca_system_score_gemma":0.0007343591,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.009021971,"about_ca_topic_score_gemma":0.01025936,"domain_scores_codex":[0.9977065,0.0007020457,0.0002240404,0.0007051673,0.0005246611,0.0001375273],"domain_scores_gemma":[0.9952435,0.001609162,0.0004054904,0.0008956463,0.001682277,0.0001639061],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004147662,0.0008918708,0.1032526,0.001567749,0.001384663,0.0007545635,0.0004702945,0.0717634,0.05889425,0.0008589824,0.06055024,0.6954638],"study_design_scores_gemma":[0.0002573429,0.0008835149,0.152413,0.0003790656,0.0003956065,0.001465775,0.0003602744,0.7559242,0.07373643,0.001468495,0.0125719,0.0001442682],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8738019,0.004800896,0.08667317,0.0009886181,0.001381166,0.0007681994,0.01420292,0.01177195,0.005611163],"genre_scores_gemma":[0.864255,0.0007859024,0.09512749,0.0004568425,0.0003041005,0.0003230151,0.03433605,0.0008926758,0.00351886],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009021971,"threshold_uncertainty_score":0.0260613,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1038954813451965,"score_gpt":0.5272726122454297,"score_spread":0.4233771309002332,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}