{"id":"W4416451430","doi":"10.1093/jimmun/vkaf283.1210","title":"Location-directed functional dichotomy of CD11c in regulating B cell tolerance 3399","year":2025,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institutes of Health","keywords":"CD11c; B cell; Germinal center; Autoimmunity; Immune tolerance; Autoantibody; Marginal zone; B-cell receptor; Peripheral tolerance","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001646701,0.0002114091,0.0001074397,0.0002934123,0.0001844899,0.0004685089,0.0002291483,0.0002828983,0.0020192],"category_scores_gemma":[0.00009588446,0.0001152284,0.00009077668,0.0001614562,0.0002789209,0.0001877632,0.0002836713,0.000525368,0.0005363582],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003390199,"about_ca_system_score_gemma":0.0002528573,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004142804,"about_ca_topic_score_gemma":0.000533979,"domain_scores_codex":[0.9998562,0.00002656459,0.000009907585,0.00003098231,0.00002590343,0.00005050062],"domain_scores_gemma":[0.9998662,0.00001592107,0.00002875385,0.00001486352,0.00001726904,0.00005700043],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001474747,0.00001950588,0.0004952899,0.00002125508,0.000002415259,0.00003170754,0.000009442704,0.00005448181,0.9969763,0.0004294906,0.00006828937,0.001744489],"study_design_scores_gemma":[0.00005428677,0.0003337649,0.01573625,0.00004295662,0.00003681121,0.0004182619,0.0001325006,0.002448809,0.9727679,0.0002499929,0.007767872,0.0000106317],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992523,0.001837877,0.001981592,0.0001597223,0.00002323171,0.00002059814,0.0002338252,0.00003921925,0.003180929],"genre_scores_gemma":[0.9966034,0.0005526452,0.0009491022,0.00005497974,0.000007859033,0.00001442971,0.0001768675,0.00001145947,0.001629284],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0020192,"threshold_uncertainty_score":0.006754875,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01364530644585718,"score_gpt":0.2828810186160515,"score_spread":0.2692357121701943,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}