{"id":"W4416469157","doi":"10.21956/gatesopenres.14417.r30072","title":"Referee report. For: Whole blood genome-wide transcriptome profiling and metagenomics next-generation sequencing in young infants with suspected sepsis in a low-and middle-income country: A study protocol [version 2; peer review: 2 approved]","year":2021,"lang":"en","type":"article","venue":"Faculty of 1000 Research Ltd","topic":"Genomics and Rare Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Grand Challenges Canada; Michael Smith Health Research BC; BC Children's Hospital; Children's Hospital Foundation; Bill and Melinda Gates Foundation","keywords":"Whole blood; Sepsis; Metagenomics; Transcriptome; Profiling (computer programming); Protocol (science)","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0142183,0.001082683,0.001830951,0.00294445,0.002944653,0.00255645,0.003116645,0.005527026,0.4514449],"category_scores_gemma":[0.1916831,0.0007554442,0.001863818,0.002419746,0.001044389,0.001922794,0.003608547,0.00491116,0.1959074],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003164589,"about_ca_system_score_gemma":0.007189835,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02870227,"about_ca_topic_score_gemma":0.03889722,"domain_scores_codex":[0.9917665,0.002708588,0.001466642,0.001122868,0.002391753,0.0005437352],"domain_scores_gemma":[0.8326341,0.05158199,0.00284647,0.00768885,0.09864867,0.006599875],"domain_codex":null,"domain_gemma":"evaluation","domain_candidate":"evaluation","domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003056705,0.00001083719,0.00007035959,0.00007510002,0.000004158338,0.00004126184,0.00002170377,0.000007717926,0.00003720359,0.000123197,0.9969065,0.002671463],"study_design_scores_gemma":[0.0002651146,0.0000458383,0.002755995,0.0005023758,0.00002936719,0.0003101271,0.0002674833,0.0001502804,0.0002802968,0.001984396,0.9933297,0.00007905177],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"editorial","genre_gemma":"commentary","genre_scores_codex":[0.001052166,0.002047016,0.007911925,0.3912441,0.4192752,0.005514885,0.1226324,0.004741138,0.04558123],"genre_scores_gemma":[0.01249724,0.00320346,0.02233221,0.3775368,0.1205738,0.01562909,0.05877976,0.005168365,0.3842793],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.9857817,"threshold_uncertainty_score":0.7824473,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05910420588915869,"score_gpt":0.3433751729347644,"score_spread":0.2842709670456057,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}