{"id":"W4416500343","doi":"10.1302/1358-992x.2025.14.021","title":"PROSPECTIVE RANDOMIZED EVALUATION OF EMERGING NOVEL TREATMENTS FOR INFECTION PROPHYLAXIS IN TOTAL JOINT REPLACEMENT (PREVENT-IT): A PILOT STUDY","year":2025,"lang":"en","type":"article","venue":"Orthopaedic Proceedings","topic":"Orthopedic Infections and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Randomized controlled trial; Chlorhexidine gluconate; Periprosthetic; Therapeutic irrigation; Chlorhexidine; Arthroplasty; Saline; Antibiotic prophylaxis; Total hip replacement","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01153868,0.002371111,0.005907033,0.0007549547,0.000869853,0.0015544,0.001773073,0.003784852,0.01157563],"category_scores_gemma":[0.01328082,0.001387164,0.004809262,0.0008414849,0.002250015,0.002317233,0.001421045,0.003152314,0.00145261],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001148441,"about_ca_system_score_gemma":0.002713053,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001175561,"about_ca_topic_score_gemma":0.001511215,"domain_scores_codex":[0.9912874,0.00603768,0.0007753935,0.0009035139,0.0004814601,0.0005145337],"domain_scores_gemma":[0.9848219,0.007027952,0.003049108,0.001592895,0.001601784,0.001906398],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9840882,0.0109676,0.0003998441,0.0004592438,0.0006760465,0.00001761459,0.00003617628,0.00009397534,0.0003320013,0.00007301302,0.0001369167,0.002719366],"study_design_scores_gemma":[0.8081664,0.1893649,0.001067624,0.00003868434,0.0006332698,0.000009415942,0.00003494479,0.0001815553,0.0001159203,0.0001001254,0.000275086,0.0000120451],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9399738,0.003767567,0.001937081,0.0007041104,0.001621086,0.0477435,0.001684713,0.0001560557,0.002412075],"genre_scores_gemma":[0.8993946,0.002221954,0.01065719,0.001617101,0.0009701693,0.08045918,0.001385641,0.0000356567,0.003258506],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01157563,"threshold_uncertainty_score":0.06102312,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03564172676647769,"score_gpt":0.3373397806079435,"score_spread":0.3016980538414658,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}