{"id":"W4416500343","doi":"10.1302/1358-992x.2025.14.021","title":"PROSPECTIVE RANDOMIZED EVALUATION OF EMERGING NOVEL TREATMENTS FOR INFECTION PROPHYLAXIS IN TOTAL JOINT REPLACEMENT (PREVENT-IT): A PILOT STUDY","year":2025,"lang":"en","type":"article","venue":"Orthopaedic Proceedings","topic":"Orthopedic Infections and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Randomized controlled trial; Chlorhexidine gluconate; Periprosthetic; Therapeutic irrigation; Chlorhexidine; Arthroplasty; Saline; Antibiotic prophylaxis; Total hip replacement","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003039215,0.0002918146,0.0008294638,0.0007551113,0.0001490571,0.00002297797,0.0000275597,0.00007302454,0.00005056208],"category_scores_gemma":[0.00103815,0.0002347618,0.000241203,0.0008951765,0.00007295419,0.0001522913,0.00005211006,0.0001740784,0.000002350205],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008140312,"about_ca_system_score_gemma":0.0003807454,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000484879,"about_ca_topic_score_gemma":0.00009274552,"domain_scores_codex":[0.9974932,0.0000546195,0.0009114475,0.00057781,0.0006654247,0.000297469],"domain_scores_gemma":[0.9983526,0.00006187838,0.0003687298,0.0001690178,0.0009767291,0.00007100849],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.05941034,0.02255552,0.8900297,0.0005197281,0.002545043,0.000003386035,0.0026609,0.00003345366,0.002716087,0.00065108,0.0001117943,0.01876292],"study_design_scores_gemma":[0.5755873,0.01959996,0.3876911,0.001078779,0.005433522,0.00003597843,0.001535059,0.005749701,0.002350785,0.0005940114,0.0000451032,0.0002986616],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9776598,0.0001074905,0.0004985847,0.0001797568,0.0003307416,0.01596911,0.000008341866,0.00006310985,0.005183066],"genre_scores_gemma":[0.9907044,0.00002682724,0.0004126487,0.00003084236,0.00007226349,0.007287804,0.00002164727,0.00002539153,0.001418217],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5161769,"threshold_uncertainty_score":0.9573306,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03564172676647769,"score_gpt":0.3373397806079435,"score_spread":0.3016980538414658,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}