{"id":"W4416500480","doi":"10.1302/1358-992x.2025.14.017","title":"THE IMPACT OF TARGETED THERAPY ON SURVIVAL AFTER SPINE METASTASIS: A SYSTEMATIC REVIEW AND POOLED DATA ANALYSIS","year":2025,"lang":"en","type":"article","venue":"Orthopaedic Proceedings","topic":"Management of metastatic bone disease","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Targeted therapy; Cancer; Meta-analysis; Lung cancer; Thyroid cancer; Overall survival; Breast cancer; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01066544,0.001798198,0.01468234,0.01280239,0.0005686374,0.002844573,0.001803475,0.001664629,0.00393205],"category_scores_gemma":[0.03216778,0.0008482477,0.02144041,0.01454661,0.000731957,0.001911475,0.001600301,0.001086908,0.0003627486],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00296217,"about_ca_system_score_gemma":0.006900334,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006976909,"about_ca_topic_score_gemma":0.01932321,"domain_scores_codex":[0.9905097,0.002741864,0.004297148,0.0009046615,0.001231547,0.0003151119],"domain_scores_gemma":[0.9751603,0.01644702,0.005090001,0.0004950131,0.002545602,0.0002619623],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.0006124399,0.00001919784,0.002976701,0.8683224,0.116633,0.0001526276,0.0001458811,0.0001913796,0.0001982912,0.0001163611,0.0006731406,0.009958649],"study_design_scores_gemma":[0.0005308812,0.0003645846,0.009458006,0.2047857,0.7785884,0.0002923767,0.0002519753,0.0001749975,0.0002010783,0.0002487131,0.005049981,0.00005333505],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005836883,0.9899408,0.0004642089,0.0001682723,0.0001020104,0.0007192091,0.002347516,0.0000160788,0.0004050694],"genre_scores_gemma":[0.1097355,0.8822003,0.001636719,0.0007639537,0.0001947618,0.002961608,0.002175714,0.00002424429,0.0003072226],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01468234,"threshold_uncertainty_score":0.05640489,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02105153504864353,"score_gpt":0.3321039094329972,"score_spread":0.3110523743843537,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}