{"id":"W4416530111","doi":"10.1016/j.neuint.2025.106091","title":"Therapeutic potential of KATP channels in the attenuation of Parkinson's disease pathogenesis and progression – A review","year":2025,"lang":"en","type":"review","venue":"Neurochemistry International","topic":"Cardiac Ischemia and Reperfusion","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada","keywords":"Pathogenesis; Dopamine; Disease; Dopaminergic; Potassium channel; Parkinson's disease; Ion channel","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002074858,0.0001833752,0.0006900002,0.00008201093,0.00001503237,0.000006593235,0.0001720804,0.0001146883,0.0000278254],"category_scores_gemma":[0.0002157204,0.0001153428,0.000380953,0.0001775395,0.00007059976,0.0000179511,0.00007915073,0.0001942796,4.713696e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002424313,"about_ca_system_score_gemma":0.0002432105,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":8.871012e-7,"about_ca_topic_score_gemma":3.333401e-8,"domain_scores_codex":[0.9986334,0.00008649796,0.0004818566,0.0002703511,0.0004468793,0.0000809482],"domain_scores_gemma":[0.9991077,0.0001109437,0.000341458,0.0002600824,0.0001415623,0.00003825057],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000763245,0.000241481,0.0002754186,0.1667356,0.0001169867,0.00007405529,0.00002359517,4.647626e-7,0.004887723,0.00001218725,0.0004540812,0.8271021],"study_design_scores_gemma":[0.0007473471,0.0000493822,0.0007670152,0.2856438,0.003235568,0.000322775,0.00001496784,0.00004733672,0.001404072,0.00001657582,0.7075096,0.0002415555],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0019933,0.9962095,0.00001079281,0.0005172836,0.0001921569,0.000667764,0.00006733973,0.00000585403,0.0003360277],"genre_scores_gemma":[0.009808906,0.9892219,0.00001549386,0.0001395346,0.0001494473,0.0001220813,0.0003650509,0.0000115333,0.0001660733],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8268605,"threshold_uncertainty_score":0.4703543,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01854388716456376,"score_gpt":0.3392844914430652,"score_spread":0.3207406042785014,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}