{"id":"W4416538945","doi":"10.1002/cpz1.70260","title":"Refined ChIP‐Seq Protocol for High‐Quality Chromatin Profiling in Solid Tissues Using the Complete Genomics/MGI Sequencing Platform","year":2025,"lang":"en","type":"article","venue":"Current Protocols","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Chromatin; ChIA-PET; Histone; Chromatin immunoprecipitation; ChIP-sequencing; Chromosome conformation capture; DNA sequencing; Protocol (science)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008135687,0.0003060051,0.0003614703,0.00007610393,0.0002686042,0.0001248914,0.0005172947,0.0001610769,0.000006958568],"category_scores_gemma":[0.0001378461,0.0002493297,0.0001265245,0.0001620303,0.00009610555,0.00001131898,0.0003001135,0.0002113966,0.000001964804],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002475978,"about_ca_system_score_gemma":0.0004775283,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003014789,"about_ca_topic_score_gemma":0.00007503763,"domain_scores_codex":[0.9979486,0.00009631933,0.0008196083,0.000530877,0.000135409,0.0004692033],"domain_scores_gemma":[0.9987658,0.0000398715,0.0003720976,0.0006305571,0.0001389328,0.00005275575],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003115604,0.0001431467,0.001319606,0.001575558,0.0000474601,6.261379e-7,0.0001147722,0.001694832,0.9853689,0.004219303,0.0001442605,0.005059947],"study_design_scores_gemma":[0.008426208,0.0005331609,0.00247752,0.00153407,0.00003904663,0.000008547417,0.0003249897,0.05842225,0.8582319,0.01301774,0.05588668,0.00109791],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.3179451,0.00002105063,0.01286462,0.00008063985,0.0001104604,0.6686883,0.0001034712,0.00002729759,0.0001590204],"genre_scores_gemma":[0.04914331,0.000001282477,0.0114334,0.0000895285,0.0002207173,0.9388441,0.0001676101,0.00003834537,0.00006163797],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.2701558,"threshold_uncertainty_score":0.9999959,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1246037232805757,"score_gpt":0.427374649560646,"score_spread":0.3027709262800703,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}