{"id":"W4416554477","doi":"10.1155/crh/8230549","title":"How Early Is Too Early? Use of Lineage‐Specific Chimerism in Early Detection of Donor‐Derived Malignancy After Allogeneic Stem Cell Transplant: A Case Report","year":2025,"lang":"en","type":"article","venue":"Case Reports in Hematology","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"London Health Sciences Centre; Western University","funders":"","keywords":"Pancytopenia; Malignancy; Stem cell; Hematological malignancy; Disease; Hematologic malignancy; Graft-versus-host disease; Transplantation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007918035,0.00163915,0.001353344,0.002333066,0.002373614,0.002246093,0.001409211,0.006361943,0.00114501],"category_scores_gemma":[0.004446644,0.001051932,0.001195328,0.001390724,0.002107029,0.002992958,0.00145616,0.004826798,0.0005793021],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001473149,"about_ca_system_score_gemma":0.0009323161,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002098035,"about_ca_topic_score_gemma":0.002208558,"domain_scores_codex":[0.9990157,0.000208879,0.0001373551,0.000196516,0.0001523824,0.0002891723],"domain_scores_gemma":[0.997687,0.0009314042,0.0005702759,0.0001696695,0.0001176884,0.0005239503],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.00002361474,0.00003340559,0.002781232,0.00002546915,0.000008048406,0.9941798,0.0001581353,0.00006441694,0.0005106475,0.000198807,0.0002601155,0.001756404],"study_design_scores_gemma":[0.000005069937,0.00002694086,0.0008161336,0.00001814439,0.00001568867,0.997602,0.00009464129,0.0002340679,0.0005285866,0.0001733102,0.0004758398,0.000009512127],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9346595,0.01829731,0.01409226,0.01738189,0.001135595,0.0003127,0.0001947666,0.0003504042,0.01357549],"genre_scores_gemma":[0.9868323,0.004514351,0.003807718,0.00222152,0.001316201,0.00002907918,0.00005560648,0.00005362325,0.001169685],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006361943,"threshold_uncertainty_score":0.01068848,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02054729466864296,"score_gpt":0.2491797065079447,"score_spread":0.2286324118393017,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}