{"id":"W4416554771","doi":"10.1016/j.clinthera.2025.10.006","title":"Evaluation of Colorectal Cancer Incidence in the United States From 2021 to 2024 Using a National Multi-Payer Claims Database","year":2025,"lang":"en","type":"article","venue":"Clinical Therapeutics","topic":"Colorectal Cancer Screening and Detection","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Incidence (geometry); Colorectal cancer; National database; MEDLINE; Cancer incidence","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002913053,0.00009645235,0.0002218718,0.0001671522,0.00004651137,0.00001543238,0.0001162124,0.0001049419,0.0001175388],"category_scores_gemma":[0.0007603984,0.0000715163,0.00007346795,0.001016313,0.00009182592,0.00004179378,0.00005135501,0.0003359234,0.000003410143],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002374709,"about_ca_system_score_gemma":0.0007034095,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001991047,"about_ca_topic_score_gemma":0.001757725,"domain_scores_codex":[0.997984,0.0004914864,0.0004862835,0.0002452274,0.0006724437,0.0001205706],"domain_scores_gemma":[0.9979913,0.0008803633,0.0001027826,0.0001818532,0.0008032588,0.00004048876],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.02131425,0.002987444,0.4039553,0.0001217981,0.001840095,0.00001954374,0.006610337,0.0881117,0.03193515,0.0001815913,0.001699371,0.4412235],"study_design_scores_gemma":[0.002239174,0.0004257417,0.1518243,0.0003204788,0.0004908345,0.000001394922,0.0006017433,0.840404,0.001446126,0.0006397445,0.001516145,0.00009028256],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914864,0.0006316531,0.005195207,0.001478214,0.0005248709,0.0005071114,0.00007619559,0.000009610329,0.00009074803],"genre_scores_gemma":[0.9943709,0.000243396,0.001914175,0.003180388,0.0001302186,0.00005372651,0.0000645941,0.000007603666,0.00003502245],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7522923,"threshold_uncertainty_score":0.300988,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3108775622450921,"score_gpt":0.5214539127059087,"score_spread":0.2105763504608166,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}