{"id":"W4416581177","doi":"10.3310/nihropenres.14114.1","title":"Determining the feasibility of randomising infants, children and young people to invasive and non-invasive urine sampling techniques (FROG): Protocol for a multicentre randomised controlled feasibility trial and mixed methods perspectives’ study of RCT feasibility.","year":2025,"lang":"en","type":"article","venue":"NIHR Open Research","topic":"Pediatric Urology and Nephrology Studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Oxford University Hospitals NHS Foundation Trust; Hospital for Sick Children; University of Oxford; University College London; Department of Health and Social Care; National Institute for Health and Care Research; Birmingham Women's and Children's NHS Foundation Trust; University College London Hospitals NHS Foundation Trust; University Hospitals of Leicester NHS Trust","keywords":"Protocol (science); Randomized controlled trial; Sampling (signal processing); Clinical trial; Urinary system; Urine; Randomization","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.1554627,0.006576752,0.009224672,0.004315835,0.00315925,0.005919439,0.004711819,0.01174882,0.07124952],"category_scores_gemma":[0.1972495,0.004609332,0.008186962,0.005248502,0.00558705,0.006251969,0.003685581,0.009258744,0.01719674],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.008461582,"about_ca_system_score_gemma":0.0199096,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002276757,"about_ca_topic_score_gemma":0.002982659,"domain_scores_codex":[0.8526947,0.1112582,0.01622321,0.006277543,0.007477025,0.006069382],"domain_scores_gemma":[0.8929137,0.05678811,0.0148113,0.01566126,0.01488783,0.004937829],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"not_applicable","study_design_scores_codex":[0.6858605,0.0198119,0.002784147,0.08475645,0.005712312,0.001037688,0.007227298,0.009265365,0.004089985,0.02365343,0.04577653,0.1100244],"study_design_scores_gemma":[0.7472534,0.06461836,0.0065774,0.02338405,0.002304723,0.0003275742,0.001786404,0.009434665,0.004031679,0.02131134,0.1183701,0.000600371],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.0006407311,0.00005677142,0.001170348,0.00008324105,0.0001126583,0.9973366,0.0003259022,0.00003332849,0.0002404024],"genre_scores_gemma":[0.0005397334,0.00001970323,0.001743545,0.0000436126,0.000009586082,0.9975459,0.0000319395,0.000002712787,0.00006317523],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.1554627,"threshold_uncertainty_score":0.8221753,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1289730392360563,"score_gpt":0.5090236316125393,"score_spread":0.380050592376483,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}