{"id":"W4416589921","doi":"10.1038/s41590-025-02328-y","title":"TSLP links intestinal nutrient sensing with amplification of the ILC2–tuft cell circuit","year":2025,"lang":"en","type":"article","venue":"Nature Immunology","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"National Institute of Allergy and Infectious Diseases; National Heart, Lung, and Blood Institute","keywords":"Thymic stromal lymphopoietin; Innate lymphoid cell; Enteroendocrine cell; Receptor; Cytokine; Crypt; Cell; Stromal cell; Cell type","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001146561,0.0004522445,0.0001898358,0.0002513411,0.0001932283,0.0004105559,0.0001647249,0.0003210552,0.001355815],"category_scores_gemma":[0.000109596,0.0001170965,0.0001936399,0.0001238051,0.0003678654,0.0003021864,0.0004154035,0.0007763706,0.0002505692],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000339914,"about_ca_system_score_gemma":0.000185342,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002788141,"about_ca_topic_score_gemma":0.0005172806,"domain_scores_codex":[0.9998538,0.00002587725,0.000005561933,0.00002653647,0.00004226176,0.00004581131],"domain_scores_gemma":[0.9998653,0.00001805185,0.00004095287,0.00001337005,0.00001380457,0.00004839876],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000187959,0.00001158622,0.0005187985,0.00002490809,0.000002613201,0.0001526088,0.00001875224,0.00006494922,0.9972497,0.0002760056,0.00004468677,0.001447389],"study_design_scores_gemma":[0.00004506294,0.0004868669,0.02328817,0.0000173496,0.00001942085,0.000707713,0.0001532778,0.002027826,0.9691075,0.0004412227,0.003697333,0.000008197569],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992724,0.001559117,0.003105213,0.0002273308,0.00003216565,0.00001232128,0.000090332,0.00009223961,0.002157254],"genre_scores_gemma":[0.9968382,0.0004974432,0.001098382,0.00006643451,0.00002531424,0.0000181176,0.00009664164,0.000009055092,0.001350412],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001355815,"threshold_uncertainty_score":0.004535675,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005456791935191909,"score_gpt":0.2076115787857721,"score_spread":0.2021547868505802,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}