{"id":"W4416612135","doi":"10.5256/f1000research.19125.r42238","title":"Referee report. For: Functional proteomic profiling reveals KLK13 and TMPRSS11D as active proteases in the lower female reproductive tract [version 2; referees: 2 approved]","year":2019,"lang":"en","type":"article","venue":"Faculty of 1000 Research Ltd","topic":"Coagulation, Bradykinin, Polyphosphates, and Angioedema","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Queen's University; Queen's University Belfast","keywords":"Female Reproductive Tract; Proteases; Reproductive tract; Proteomics; Profiling (computer programming)","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.004577089,0.001108129,0.001390674,0.004289397,0.003617845,0.003160859,0.003059447,0.007281824,0.4365334],"category_scores_gemma":[0.04737831,0.0007540931,0.001767636,0.002411877,0.0007471553,0.001993232,0.002584927,0.004026783,0.2052425],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00298124,"about_ca_system_score_gemma":0.004534415,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02735695,"about_ca_topic_score_gemma":0.03912736,"domain_scores_codex":[0.9955649,0.0004319128,0.0004725952,0.0005658344,0.002567034,0.000397756],"domain_scores_gemma":[0.9468352,0.008734557,0.001229257,0.002533242,0.03839434,0.002273354],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001634235,0.00001473908,0.00004424929,0.00003846935,0.000003045466,0.00005482128,0.00001074123,0.000008026067,0.0001817118,0.0001635805,0.9963416,0.003122589],"study_design_scores_gemma":[0.00006482669,0.00003344188,0.001870912,0.0001207641,0.00001680385,0.0001840997,0.00006551051,0.000105931,0.0006815658,0.001024631,0.9957823,0.00004930795],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"editorial","genre_gemma":"other","genre_scores_codex":[0.001160669,0.004595437,0.006654229,0.2382434,0.5614806,0.002245354,0.04990947,0.007773871,0.127937],"genre_scores_gemma":[0.007594302,0.003426314,0.006678283,0.09524171,0.06227152,0.001390027,0.02266749,0.002540122,0.7981902],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.4365334,"threshold_uncertainty_score":0.8037167,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06895305416310524,"score_gpt":0.3692838875211077,"score_spread":0.3003308333580025,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}