{"id":"W4416612135","doi":"10.5256/f1000research.19125.r42238","title":"Referee report. For: Functional proteomic profiling reveals KLK13 and TMPRSS11D as active proteases in the lower female reproductive tract [version 2; referees: 2 approved]","year":2019,"lang":"en","type":"article","venue":"Faculty of 1000 Research Ltd","topic":"Coagulation, Bradykinin, Polyphosphates, and Angioedema","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Queen's University; Queen's University Belfast","keywords":"Female Reproductive Tract; Proteases; Reproductive tract; Proteomics; Profiling (computer programming)","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003894313,0.0002263087,0.0004722225,0.0002886323,0.0002253922,0.00004410575,0.0001992999,0.0001926918,0.0001492491],"category_scores_gemma":[0.003528521,0.0001579299,0.0001568423,0.0004420782,0.0002318566,0.0003208768,0.0001101326,0.0006006328,0.00004680729],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002018163,"about_ca_system_score_gemma":0.0005053511,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005494319,"about_ca_topic_score_gemma":0.00003152839,"domain_scores_codex":[0.9964626,0.0003005375,0.000554831,0.0008763011,0.001294502,0.0005111858],"domain_scores_gemma":[0.9968963,0.0004852015,0.0002670814,0.0007922648,0.001431725,0.0001273945],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0309449,0.005383078,0.5308435,0.004003432,0.0006931245,0.0003419282,0.01132152,0.00006562319,0.3558748,0.00567531,0.03283034,0.02202247],"study_design_scores_gemma":[0.006000653,0.005072831,0.7587093,0.001587858,0.0001140495,0.0004403843,0.01030684,0.0002172953,0.1614768,0.003942195,0.05160511,0.0005267328],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9827929,0.0003227852,0.00001967888,0.006916893,0.00007937454,0.006184664,0.0001413596,0.0000332977,0.003509086],"genre_scores_gemma":[0.9701552,0.00004183891,0.0007138946,0.00005986725,0.0002784705,0.0005088494,0.0007033999,0.0000337407,0.02750477],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2278658,"threshold_uncertainty_score":0.6440195,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06895305416310524,"score_gpt":0.3692838875211077,"score_spread":0.3003308333580025,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}