{"id":"W4416636859","doi":"10.1183/13993003.congress-2025.rct1114","title":"Efficacy and Safety of Dupilumab (DUP) vs Omalizumab (OMA) in Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) with Asthma (EVEREST study)","year":2025,"lang":"","type":"article","venue":"","topic":"Sinusitis and nasal conditions","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Hospital Foundation","funders":"","keywords":"Asthma; Nasal polyps; Nasal congestion; dup; Adverse effect; Omalizumab; Quality of life (healthcare); Dupilumab","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001941284,0.0006304916,0.001864286,0.0002541908,0.0002733175,0.0009044834,0.0005728782,0.001290644,0.002613888],"category_scores_gemma":[0.001517063,0.0004974728,0.00182737,0.0002262924,0.0004812986,0.0007983973,0.0003940157,0.001975312,0.0004905597],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004998458,"about_ca_system_score_gemma":0.0005923714,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008945785,"about_ca_topic_score_gemma":0.002453927,"domain_scores_codex":[0.9993405,0.0003366263,0.00005556006,0.00009616136,0.00006255018,0.0001086288],"domain_scores_gemma":[0.9990709,0.0003072202,0.0002538981,0.00004791144,0.00004450659,0.0002754521],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9419644,0.004308027,0.003127411,0.0009160766,0.001390737,0.00008137698,0.00008105508,0.0004157084,0.004687117,0.00005772847,0.001172745,0.04179749],"study_design_scores_gemma":[0.5233116,0.4391702,0.02860632,0.0001594848,0.003071878,0.0003919402,0.0001094563,0.00102892,0.001642665,0.0001374591,0.002317729,0.00005228396],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902487,0.007568941,0.00008503796,0.000321139,0.0001881581,0.0002190097,0.000491428,0.00002445126,0.0008531825],"genre_scores_gemma":[0.9944728,0.002588538,0.0003030977,0.0005306128,0.0002712944,0.0003110705,0.0006874073,0.000007900153,0.000827382],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002613888,"threshold_uncertainty_score":0.0102666,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007806897011503707,"score_gpt":0.2659436235662796,"score_spread":0.2581367265547759,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}