{"id":"W4416637157","doi":"10.1183/13993003.congress-2025.rct5335","title":"RCT Abstract - ENV-101 for the treatment of idiopathic pulmonary fibrosis: a randomised, double-blind, placebo-controlled phase 2 trial","year":2025,"lang":"","type":"article","venue":"","topic":"Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Dysgeusia; Idiopathic pulmonary fibrosis; Placebo; Adverse effect; Vital capacity; Discontinuation; Pulmonary function testing; Population; Clinical trial","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002831339,0.001786172,0.002845571,0.0004198982,0.0006241014,0.001389548,0.0008205675,0.003795546,0.03716924],"category_scores_gemma":[0.004160561,0.0006595624,0.002894487,0.000473247,0.0008260183,0.001455962,0.0004886891,0.002828524,0.003713615],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008163747,"about_ca_system_score_gemma":0.001667438,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009696892,"about_ca_topic_score_gemma":0.002223377,"domain_scores_codex":[0.9986203,0.0007719068,0.000132575,0.0002277767,0.0001288573,0.0001186615],"domain_scores_gemma":[0.9987244,0.0003890895,0.0003408333,0.0001108623,0.0001801615,0.0002545938],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9618701,0.002904908,0.0003242798,0.007295252,0.00288047,0.00006683074,0.00004386175,0.0001664884,0.001793421,0.0003286966,0.00650961,0.01581599],"study_design_scores_gemma":[0.9854043,0.01049239,0.0005689761,0.0002748212,0.0005583368,0.00002302577,0.00001008166,0.00009709469,0.00009668858,0.0001612804,0.002304084,0.000008896506],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.587178,0.09375507,0.007857428,0.01321846,0.01445255,0.1861751,0.04519654,0.001693069,0.05047379],"genre_scores_gemma":[0.7904182,0.02349241,0.01081537,0.01523243,0.003421318,0.1130866,0.01220894,0.0001568934,0.03116788],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03716924,"threshold_uncertainty_score":0.1243435,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03249179019170925,"score_gpt":0.3367372662485669,"score_spread":0.3042454760568576,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}