{"id":"W4416637876","doi":"10.1183/13993003.congress-2025.pa4576","title":"Effect of add-on dupilumab in elderly patients with chronic obstructive pulmonary disease: BOREAS and NOTUS","year":2025,"lang":"","type":"article","venue":"","topic":"Chronic Obstructive Pulmonary Disease (COPD) Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Research Canada","funders":"","keywords":"Dupilumab; Exacerbation; Placebo; COPD; Quality of life (healthcare); Lung function; Pulmonary function testing; Clinical endpoint","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001144837,0.000629051,0.001358013,0.000216549,0.0003577851,0.0008062941,0.0005047134,0.0008560806,0.006662791],"category_scores_gemma":[0.00187033,0.0001875655,0.002620476,0.000183189,0.0003236218,0.0007569852,0.000470505,0.0012985,0.0005982327],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007354768,"about_ca_system_score_gemma":0.0009841232,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001981868,"about_ca_topic_score_gemma":0.009007948,"domain_scores_codex":[0.9995996,0.0001692941,0.00004317302,0.00006237498,0.00004545685,0.00008017145],"domain_scores_gemma":[0.9990605,0.0001929568,0.0001902746,0.00007335944,0.0001159564,0.0003669481],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.6723342,0.008417475,0.006199239,0.003279931,0.003225894,0.0002723192,0.0002526257,0.0009165985,0.009850636,0.000801906,0.01608554,0.2783636],"study_design_scores_gemma":[0.4790204,0.3416298,0.09800813,0.001481432,0.009051167,0.001332187,0.0005179952,0.003167989,0.004772785,0.001483818,0.05933063,0.0002036488],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.949268,0.02763193,0.0003417415,0.003291043,0.001606033,0.0008878981,0.003042079,0.0002324406,0.01369883],"genre_scores_gemma":[0.9855375,0.004891142,0.00104886,0.002982803,0.0004014606,0.0004987805,0.001647522,0.00002149414,0.002970495],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006662791,"threshold_uncertainty_score":0.02228922,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004344361766929917,"score_gpt":0.2616691397687321,"score_spread":0.2573247780018022,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}