{"id":"W4416638699","doi":"10.1183/13993003.congress-2025.oa1197","title":"Single-cell RNA sequencing of small airways of young persons who use e-cigarettes","year":2025,"lang":"","type":"article","venue":"","topic":"Single-cell and spatial transcriptomics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital","funders":"","keywords":"Immune system; RNA; Airway; Cell; Lung; Basal (medicine); Small airways","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002762975,0.0005091559,0.0007501522,0.0002047659,0.0001391036,0.00006931533,0.0005377114,0.0006506658,0.00009084652],"category_scores_gemma":[0.0001711381,0.0005284055,0.0005767199,0.0003808701,0.0004766991,0.00001515282,0.000205793,0.0002880524,0.0000014342],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009339792,"about_ca_system_score_gemma":0.000620293,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001065663,"about_ca_topic_score_gemma":0.0003938417,"domain_scores_codex":[0.9972386,0.0001404416,0.001039671,0.0007605178,0.0002346458,0.0005861293],"domain_scores_gemma":[0.9980874,0.0001039668,0.0003816769,0.0008215773,0.0004607459,0.0001446047],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002285745,0.0004949637,0.01213853,0.000534826,0.0002701895,0.000004714147,0.0007056986,0.0001633871,0.9805492,0.0004106955,0.0007291801,0.003769997],"study_design_scores_gemma":[0.001325815,0.000733593,0.0004295188,0.0004166622,0.0003103693,0.000004163135,0.001151811,0.001440717,0.9904019,0.00003073592,0.003286746,0.0004680101],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9431654,0.003135014,0.01360228,0.0001553203,0.0006982087,0.0003752334,0.0001584074,0.00001814158,0.03869201],"genre_scores_gemma":[0.9828224,0.0008408122,0.002764802,0.0003026637,0.0001060858,0.000006186143,0.00006786309,0.00005129111,0.01303791],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.039657,"threshold_uncertainty_score":0.9997168,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02725268817727512,"score_gpt":0.2221360465163494,"score_spread":0.1948833583390743,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}